Macrophage-Specific IGF-1 Overexpression Reduces CXCL12 Chemokine Levels and Suppresses Atherosclerotic Burden in Apoe-Deficient Mice
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DOI: 10.1161/atvbaha.121.316090
Abstract: Supplemental Digital Content is available in the text. Objective: IGF-1 (insulin-like growth factor 1) exerts pleiotropic effects including promotion of cellular growth, differentiation, survival, and anabolism. We have shown that systemic IGF-1 administration reduced atherosclerosis… read more here.
Keywords: macrophage; macrophage specific; atherosclerotic burden; igf overexpression ... See more keywords