Bile acids initiate cholestatic liver injury by triggering a hepatocyte-specific inflammatory response.
Sign Up to like & getrecommendations! Published in 2017 at "JCI insight"
DOI: 10.1172/jci.insight.90780
Abstract: Mechanisms of bile acid-induced (BA-induced) liver injury in cholestasis are controversial, limiting development of new therapies. We examined how BAs initiate liver injury using isolated liver cells from humans and mice and in-vivo mouse models.… read more here.
Keywords: liver injury; injury; hepatocyte specific; specific inflammatory ... See more keywords
Regional variances depict a unique glial-specific inflammatory response following closed-head injury
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2023.1076851
Abstract: Mild traumatic brain injuries (mTBI) constitute a significant health concern with clinical symptoms ranging from headaches to cognitive deficits. Despite the myriad of symptoms commonly reported following this injury, there is still a lack of… read more here.
Keywords: specific inflammatory; closed head; inflammatory response; glial specific ... See more keywords