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Published in 2020 at "ACS medicinal chemistry letters"
DOI: 10.1021/acsmedchemlett.9b00526
Abstract: Gatastatin (O 7-benzyl glaziovianin A) is a γ-tubulin-specific inhibitor that is used to investigate γ-tubulin function in cells. We have previously reported that the unsubstituted phenyl ring of the O 7-benzyl group in gatastatin is…
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Keywords:
tubulin specific;
structure optimization;
gatastatin;
specific inhibitor ... See more keywords
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Published in 2018 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02233-18
Abstract: Candida auris is an emerging pathogen associated with significant mortality and often multidrug resistance. VT-1598, a tetrazole-based fungal CYP51-specific inhibitor, was evaluated in vitro and in vivo against C. auris. ABSTRACT Candida auris is an…
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Keywords:
vitro vivo;
specific inhibitor;
candida auris;
fungal cyp51 ... See more keywords
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Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/4539932
Abstract: Objective Ischemic heart disease (IHD) has always been the focus of attention of many researchers in cardiovascular disease, and its pathogenesis is also very complicated. Ferroptosis may be involved in the occurrence and development of…
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Keywords:
ferroptosis specific;
nrf2 pathway;
inhibitor ferrostatin;
primary cardiomyocytes ... See more keywords