A Novel Approach to Estimate ROS Origination by Hyperbaric Oxygen Exposure, Targeted Probes and Specific Inhibitors
Sign Up to like & getrecommendations! Published in 2018 at "Cellular Physiology and Biochemistry"
DOI: 10.1159/000491061
Abstract: Background/Aims: Reactive oxygen species (ROS) are considered fundamental in various physiological/pathophysiological processes and prevention/treatment measures such as hyperbaric oxygen (HBO) therapy. In this study, the origination of ROS in human umbilical vein endothelial cells was… read more here.
Keywords: oxygen; whole cell; hbo; specific inhibitors ... See more keywords
Combinatorial engineering of N-TIMP2 variants that selectively inhibit MMP9 and MMP14 function in the cell
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.25885
Abstract: Developing selective inhibitors for proteolytic enzymes that share high sequence homology and structural similarity is important for achieving high target affinity and functional specificity. Here, we used a combination of yeast surface display and dual-color… read more here.
Keywords: specific inhibitors; mmp9 mmp14; target; mmp14 ... See more keywords
Inhibition of Rumen Protozoa by Specific Inhibitors of Lysozyme and Peptidases in vitro
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2019.02822
Abstract: Defaunation studies have shown that rumen protozoa are one of the main causes of low nitrogen utilization efficiency due to their bacterivory and subsequent intraruminal cycling of microbial protein in ruminants. In genomic and transcriptomic… read more here.
Keywords: inhibitor; lysozyme peptidases; specific inhibitors; inhibition ... See more keywords
RET Proto-Oncogene—Not Such an Obvious Starting Point in Cancer Therapy
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DOI: 10.3390/cancers14215298
Abstract: Simple Summary Rearranged during transfection (RET) is a transmembrane receptor tyrosine kinase that shows targetable mutations and gene fusions in a few types of cancers. Multiple kinase inhibitors, which target RET kinase, show little efficiency… read more here.
Keywords: ret specific; specific inhibitors; kinase; ret ... See more keywords