Regulation of cofilin phosphorylation in glomerular podocytes by testis specific kinase 1 (TESK1)
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DOI: 10.1038/s41598-018-30115-3
Abstract: Expression of a constitutively active Rho A (V14Rho) in podocytes in vivo induces albuminuria and foot process (FP) effacement. These effects may be mediated by the Rho A effector Rho kinase (ROK); but inhibition of… read more here.
Keywords: specific kinase; cfl1; kinase; testis specific ... See more keywords
Passive transfer models of myasthenia gravis with muscle‐specific kinase antibodies
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DOI: 10.1111/nyas.13543
Abstract: Myasthenia gravis (MG) with antibodies to muscle‐specific kinase (MuSK) is characterized by fluctuating fatigable weakness. In MuSK MG, involvement of bulbar muscles, neck, and shoulder and respiratory weakness are more prominent than in acetylcholine receptor… read more here.
Keywords: specific kinase; passive transfer; myasthenia gravis; muscle specific ... See more keywords
Vector‐mediated expression of muscle specific kinase restores specific force to muscles in the mdx mouse model of Duchenne muscular dystrophy
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DOI: 10.1113/ep089439
Abstract: What is the central question of this study? The (dystrophin‐deficient) muscles of mdx mice generate less contractile force per cross‐sectional area (specific force) than those of healthy wild‐type mice: what is the influence of muscle… read more here.
Keywords: muscle; muscle specific; muscles mdx; force ... See more keywords
Muscle-Specific Kinase Myasthenia Gravis
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.00707
Abstract: Thirty to fifty percent of patients with acetylcholine receptor (AChR) antibody (Ab)-negative myasthenia gravis (MG) have Abs to muscle specific kinase (MuSK) and are referred to as having MuSK-MG. MuSK is a 100 kD single-pass… read more here.
Keywords: specific kinase; muscle; kinase; myasthenia gravis ... See more keywords
Internalization of Muscle-Specific Kinase Is Increased by Agrin and Independent of Kinase-Activity, Lrp4 and Dynamin
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DOI: 10.3389/fnmol.2022.780659
Abstract: Muscle-specific kinase (MuSK) is a receptor tyrosine kinase absolutely required for neuromuscular junction formation. MuSK is activated by binding of motor neuron-derived Agrin to low-density lipoprotein receptor related protein 4 (Lrp4), which forms a complex… read more here.
Keywords: internalization; muscle specific; kinase; specific kinase ... See more keywords
MuSK (Muscle Specific Kinase) Positive Myasthenia: Grave Prognosis or Undue Prejudice?
Sign Up to like & getrecommendations! Published in 2020 at "Annals of Indian Academy of Neurology"
DOI: 10.4103/aian.aian_302_19
Abstract: Objectives: Patients with muscle-specific kinase (MuSK)-positive myasthenia are generally considered to have a grave prognosis. We present our experience of patients with myasthenia with different antibody status. This is followed by a short discourse on… read more here.
Keywords: prognosis; muscle specific; myasthenia; positive myasthenia ... See more keywords