Processivity and specificity of histone acetylation by the male-specific lethal complex
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DOI: 10.1093/nar/gkae123
Abstract: Abstract Acetylation of lysine 16 of histone H4 (H4K16ac) stands out among the histone modifications, because it decompacts the chromatin fiber. The metazoan acetyltransferase MOF (KAT8) regulates transcription through H4K16 acetylation. Antibody-based studies had yielded… read more here.
Keywords: specific lethal; processivity; male specific; acetylation ... See more keywords
The Non-Specific Lethal (NSL) Histone Acetyltransferase Complex Transcriptionally Regulates Yin Yang 1-Mediated Cell Proliferation in Human Cells
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DOI: 10.3390/ijms23073801
Abstract: The human males absent on the first (MOF)-containing non-specific lethal (NSL) histone acetyltransferase (HAT) complex acetylates histone H4 at lysine K5, K8, and K16. This complex shares several subunits with other epigenetic regulatory enzymes, which… read more here.
Keywords: cell; nsl; specific lethal; non specific ... See more keywords