Combinatorial Screening of Peptides, Specific Ligands of Death Receptor DR5
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3809-8
Abstract: Death receptors, in particular DR5, are highly attractive targets of antitumor therapy. The major limitation to application of natural death receptor ligands (TRAIL) is their non-specific cytotoxicity against normal cells. Since TRAIL can also bind… read more here.
Keywords: death; combinatorial screening; death receptor; screening peptides ... See more keywords
General principles of binding between cell surface receptors and multi-specific ligands: A computational study
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DOI: 10.1371/journal.pcbi.1005805
Abstract: The interactions between membrane receptors and extracellular ligands control cell-cell and cell-substrate adhesion, and environmental responsiveness by representing the initial steps of cell signaling pathways. These interactions can be spatial-temporally regulated when different extracellular ligands… read more here.
Keywords: surface receptors; general principles; cell; multi specific ... See more keywords
The Na/K-ATPase Signaling: From Specific Ligands to General Reactive Oxygen Species
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DOI: 10.3390/ijms19092600
Abstract: The signaling function of the Na/K-ATPase has been established for 20 years and is widely accepted in the field, with many excellent reports and reviews not cited here. Even though there is debate about the… read more here.
Keywords: reactive oxygen; signaling specific; atpase signaling; oxygen species ... See more keywords