Postweaning positive modulation of α5GABAA receptors improves autism‐like features in prenatal valproate rat model in a sex‐specific manner
Sign Up to like & getrecommendations! Published in 2022 at "Autism Research"
DOI: 10.1002/aur.2699
Abstract: Autism spectrum disorder (ASD), as a common neurodevelopmental disorder that encompasses impairments in social communication and interaction, as well as repetitive and restrictive behavior, still awaits an effective treatment strategy. The involvement of GABAergic neurotransmission,… read more here.
Keywords: specific manner; autism; iii 022; sex specific ... See more keywords
Exposure of cigarette smoke condensate activates NLRP3 inflammasome in THP-1 cells in a stage-specific manner: An underlying role of innate immunity in atherosclerosis.
Sign Up to like & getrecommendations! Published in 2020 at "Cellular signalling"
DOI: 10.1016/j.cellsig.2020.109645
Abstract: BACKGROUND Smoking is known to affect all the phases of atherosclerosis, thus is considered as an independent and major risk factor. The underlying mechanism responsible for the atherogenic effects of smoking is still uncertain and… read more here.
Keywords: csc; specific manner; exposure; stage specific ... See more keywords
Adolescent Stress Disrupts the Maturation of Anxiety-related Behaviors and Alters the Developmental Trajectory of the Prefrontal Cortex in a Sex- and Age-specific Manner
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.08.030
Abstract: Adolescence is a window of vulnerability to environmental factors such as chronic stress that can disrupt brain development and cause long-lasting behavioral dysfunction, as seen in disorders like depression, anxiety, and schizophrenia. There are also… read more here.
Keywords: specific manner; adolescent stress; anxiety; adolescence ... See more keywords
Prenatal exposure to Zika virus shapes offspring neutrophil function in a sex-specific manner
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-63941-x
Abstract: Maternal viral infection during pregnancy can have lasting consequences on offspring immune development. Zika virus (ZIKV) is known to trigger maternal immune activation (MIA), yet its impact on fetal and postnatal innate immunity remains poorly… read more here.
Keywords: sex specific; sex; infection; zika virus ... See more keywords
Controlling liquid-liquid phase separation of G-quadruplex-forming RNAs in a sequence-specific manner.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04366a
Abstract: We constructed a minimum liquid-liquid phase separation model system to form liquid droplets using only G-quadruplex-forming oligonucleotides and R- and G-rich oligopeptides. We found that the G-quadruplex structure is an essential component for RNA to… read more here.
Keywords: specific manner; liquid phase; quadruplex forming; phase separation ... See more keywords
An Aphid Effector Targets Trafficking Protein VPS52 in a Host-Specific Manner to Promote Virulence1[OPEN]
Sign Up to like & getrecommendations! Published in 2017 at "Plant Physiology"
DOI: 10.1104/pp.16.01458
Abstract: A secreted salivary protein from an herbivorous insect targets a protein in host plants to promote infestation. Plant- and animal-feeding insects secrete saliva inside their hosts, containing effectors, which may promote nutrient release and suppress… read more here.
Keywords: insects; specific manner; plant; host ... See more keywords
Senescence‐associated transcriptional derepression in subtelomeres is determined in a chromosome‐end‐specific manner
Sign Up to like & getrecommendations! Published in 2023 at "Aging Cell"
DOI: 10.1111/acel.13804
Abstract: Aging is a continuous process leading to physiological deterioration with age. One of the factors contributing to aging is telomere shortening, causing alterations in the protein protective complex named shelterin and replicative senescence. Here, we… read more here.
Keywords: specific manner; chromosome end; end specific; senescence ... See more keywords
PhoPR Contributes to Staphylococcus aureus Growth during Phosphate Starvation and Pathogenesis in an Environment-Specific Manner
Sign Up to like & getrecommendations! Published in 2018 at "Infection and Immunity"
DOI: 10.1128/iai.00371-18
Abstract: Microbial pathogens must obtain all essential nutrients, including phosphate, from the host. To optimize phosphate acquisition in diverse and dynamic environments, such as mammalian tissues, many bacteria use the PhoPR two-component system. ABSTRACT Microbial pathogens… read more here.
Keywords: staphylococcus aureus; specific manner; environment specific; phopr ... See more keywords
Viral Inactivation Impacts Microbiome Estimates in a Tissue-Specific Manner
Sign Up to like & getrecommendations! Published in 2021 at "mSystems"
DOI: 10.1128/msystems.00674-21
Abstract: Understanding how viral infections impact and are modulated by the microbiome is an important problem in basic research but is also of high clinical relevance under the current pandemic. To facilitate the study of interactions… read more here.
Keywords: tissue specific; inactivation; study; specific manner ... See more keywords
Early-life stress affects Mongolian gerbil interactions with conspecific vocalizations in a sex-specific manner
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2023.1128586
Abstract: During development, early-life stress (ELS) impairs cognition, learning, and emotional regulation, in part by disrupting neural circuitry in regions underlying these higher-order functions. In addition, our recent work indicates that ELS also alters simple sensory… read more here.
Keywords: conspecific vocalizations; specific manner; early life; sex ... See more keywords
A Compendium of G-Flipon Biological Functions That Have Experimental Validation
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms251910299
Abstract: As with all new fields of discovery, work on the biological role of G-quadruplexes (GQs) has produced a number of results that at first glance are quite baffling, sometimes because they do not fit well… read more here.
Keywords: sequence specific; sequence; biological functions; specific manner ... See more keywords