Region-specific mechanisms of corticosteroid-mediated inotropy in rat cardiomyocytes
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68308-4
Abstract: Regional differences in ion channel activity in the heart control the sequence of repolarization and may contribute to differences in contraction. Corticosteroids such as aldosterone or corticosterone increase the L-type Ca2+ current (ICaL) in the… read more here.
Keywords: mechanisms corticosteroid; corticosteroid mediated; specific mechanisms; region specific ... See more keywords
Multiplatform analysis of DCT-specific mechanisms during low dietary potassium intake
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5732301
Abstract: Western diets are typically high in sodium, widely regarded to increase blood pressure (BP). They are also characterised by a relatively low potassium (K) intake, also linked to higher BP. Previous studies have shown that… read more here.
Keywords: low dietary; physiology; dct specific; specific mechanisms ... See more keywords
Organelle-Specific Mechanisms in Crosstalk between Apoptosis and Ferroptosis
Sign Up to like & getrecommendations! Published in 2023 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2023/3400147
Abstract: Apoptosis has been extensively studied, whereas ferroptosis is a newly discovered form of regulated cell death that involves iron-dependent accumulations of lipid hydroperoxides. While these two cell death mechanisms were initially believed to be mutually… read more here.
Keywords: organelle specific; apoptosis; crosstalk apoptosis; apoptosis ferroptosis ... See more keywords
Cell-Specific Mechanisms in the Heart of COVID-19 Patients
Sign Up to like & getrecommendations! Published in 2023 at "Circulation Research"
DOI: 10.1161/circresaha.123.321876
Abstract: From the onset of the pandemic, evidence of cardiac involvement in acute COVID-19 abounded. Cardiac presentations ranged from arrhythmias to ischemia, myopericarditis/myocarditis, ventricular dysfunction to acute heart failure, and even cardiogenic shock. Elevated serum cardiac… read more here.
Keywords: cell; covid; specific mechanisms; heart ... See more keywords
Investigating patient-specific mechanisms of change in SET vs. EFT for depression: study protocol for a mechanistic randomized controlled trial
Sign Up to like & getrecommendations! Published in 2021 at "BMC Psychiatry"
DOI: 10.1186/s12888-021-03279-y
Abstract: Background Major depressive disorder (MDD) is the leading cause of disability worldwide and one of the most heterogeneous mental health disorders. Although there are effective treatments for MDD, about 50% of patients do not respond… read more here.
Keywords: patient specific; trial; specific mechanisms; treatment ... See more keywords
Specific mechanisms of translation initiation in higher eukaryotes: the eIF4G2 story
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DOI: 10.1261/rna.079462.122
Abstract: The eukaryotic initiation factor 4G2 (eIF4G2, DAP5, Nat1, p97) was discovered in 1997. Over the past two decades, dozens of papers have presented contradictory data on eIF4G2 function. Since its identification, eIF4G2 has been assumed… read more here.
Keywords: eif4g2; specific mechanisms; translation initiation; higher eukaryotes ... See more keywords