HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection
Sign Up to like & getrecommendations! Published in 2017 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2017.05.029
Abstract: HIV-specific broadly neutralizing antibodies (bnAbs) have been isolated from patients with high viremia but also from HIV controllers that repress HIV-1 replication. In these elite controllers (ECs), multiple parameters contribute to viral suppression, including genetic… read more here.
Keywords: memory cells; hiv; specific memory; hiv specific ... See more keywords
The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis
Sign Up to like & getrecommendations! Published in 2021 at "Nature Immunology"
DOI: 10.1038/s41590-021-01090-1
Abstract: Antigen-specific memory CD4 + T cells can persist and confer rapid and efficient protection from microbial reinfection. However, the mechanisms underlying the long-term maintenance of the memory CD4 + T cell pool remain largely unknown.… read more here.
Keywords: cd4 cells; memory; virus; memory cd4 ... See more keywords
SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and Postvaccination.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2022.0013
Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), has resulted in major worldwide disruption and loss of life over the last 2 years. Many research studies have shown waning serological SARS-CoV-2-specific… read more here.
Keywords: disease; cov specific; antigen specific; specific memory ... See more keywords
High activation levels maintained in receptor‐binding domain–specific memory B cells in people with severe coronavirus disease 2019
Sign Up to like & getrecommendations! Published in 2022 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12607
Abstract: The long‐term health consequences of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection are still being understood. The molecular and phenotypic properties of SARS‐CoV‐2 antigen–specific T cells suggest a dysfunctional profile that persists in convalescence… read more here.
Keywords: coronavirus disease; severe coronavirus; coronavirus; specific memory ... See more keywords
Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver
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DOI: 10.1371/journal.pone.0171826
Abstract: Whole malaria sporozoite vaccine regimens are promising new strategies, and some candidates have demonstrated high rates of durable clinical protection associated with memory T cell responses. Little is known about the anatomical distribution of memory… read more here.
Keywords: sporozoite specific; protection; immunization; memory cells ... See more keywords
The extrinsic factors important to the homeostasis of allergen-specific memory CD4 T cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1080855
Abstract: Memory T cells, which are generated after the primary immune response to cognate antigens, possess unique features compared to naïve or effector T cells. These memory T cells are maintained for a long period of… read more here.
Keywords: allergen specific; cd4 cells; specific memory; memory ... See more keywords