SARS‐CoV‐2 reinfection broadens the antibody responses and promotes the phenotypic differentiation of virus‐specific memory T cells in adolescents
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.29873
Abstract: The emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) Omicron subvariants raises concerns regarding the effectiveness of immunity acquired from previous Omicron subvariants breakthrough infections (BTIs) or reinfections (RIs) against the current circulating Omicron… read more here.
Keywords: sars cov; differentiation virus; phenotypic differentiation; virus specific ... See more keywords
HIV-Specific B Cell Frequency Correlates with Neutralization Breadth in Patients Naturally Controlling HIV-Infection
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DOI: 10.1016/j.ebiom.2017.05.029
Abstract: HIV-specific broadly neutralizing antibodies (bnAbs) have been isolated from patients with high viremia but also from HIV controllers that repress HIV-1 replication. In these elite controllers (ECs), multiple parameters contribute to viral suppression, including genetic… read more here.
Keywords: memory cells; hiv; specific memory; hiv specific ... See more keywords
The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis
Sign Up to like & getrecommendations! Published in 2021 at "Nature Immunology"
DOI: 10.1038/s41590-021-01090-1
Abstract: Antigen-specific memory CD4 + T cells can persist and confer rapid and efficient protection from microbial reinfection. However, the mechanisms underlying the long-term maintenance of the memory CD4 + T cell pool remain largely unknown.… read more here.
Keywords: cd4 cells; memory; virus; memory cd4 ... See more keywords
SARS-CoV-2-Specific Memory B Cell Responses Are Maintained After Recovery from Natural Infection and Postvaccination.
Sign Up to like & getrecommendations! Published in 2022 at "Viral immunology"
DOI: 10.1089/vim.2022.0013
Abstract: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), has resulted in major worldwide disruption and loss of life over the last 2 years. Many research studies have shown waning serological SARS-CoV-2-specific… read more here.
Keywords: disease; cov specific; antigen specific; specific memory ... See more keywords
High activation levels maintained in receptor‐binding domain–specific memory B cells in people with severe coronavirus disease 2019
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DOI: 10.1111/imcb.12607
Abstract: The long‐term health consequences of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection are still being understood. The molecular and phenotypic properties of SARS‐CoV‐2 antigen–specific T cells suggest a dysfunctional profile that persists in convalescence… read more here.
Keywords: coronavirus disease; severe coronavirus; coronavirus; specific memory ... See more keywords
Chemoprophylaxis with sporozoite immunization in P. knowlesi rhesus monkeys confers protection and elicits sporozoite-specific memory T cells in the liver
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0171826
Abstract: Whole malaria sporozoite vaccine regimens are promising new strategies, and some candidates have demonstrated high rates of durable clinical protection associated with memory T cell responses. Little is known about the anatomical distribution of memory… read more here.
Keywords: sporozoite specific; protection; immunization; memory cells ... See more keywords
The extrinsic factors important to the homeostasis of allergen-specific memory CD4 T cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1080855
Abstract: Memory T cells, which are generated after the primary immune response to cognate antigens, possess unique features compared to naïve or effector T cells. These memory T cells are maintained for a long period of… read more here.
Keywords: allergen specific; cd4 cells; specific memory; memory ... See more keywords
Optimizing PBMC Cryopreservation and Utilization for ImmunoSpot® Analysis of Antigen-Specific Memory B Cells
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DOI: 10.3390/vaccines13070765
Abstract: Background: Measuring frequencies of antigen-specific memory B cells (Bmem), their immunoglobulin (Ig) class and subclass usage, cross-reactivity, and affinity can provide insights into the efficacy of future antibody responses in case of antigen re-encounter. B… read more here.
Keywords: antigen specific; cell; memory cells; specific memory ... See more keywords
Multiplexed Antibody Sequencing and Profiling of the Human Hemagglutinin-specific Memory B Cell Response following Influenza Vaccination.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of immunology"
DOI: 10.4049/jimmunol.2400326
Abstract: Influenza virus is a highly contagious respiratory pathogen causing between 9.4 and 41 million infections per year in the United States in the last decade. Annual vaccination is recommended by the World Health Organization, with… read more here.
Keywords: influenza; response; cell; vaccination ... See more keywords