In silico designing of a new cysteine analogue of hirudin variant 3 for site specific PEGylation
Sign Up to like & getrecommendations! Published in 2017 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.199048
Abstract: Hirudin is an anticoagulant agent of the salivary glands of the medicinal leech. Recombinant hirudin (r-Hir) displays certain drawbacks including bleeding and immunogenicity. To solve these problems, cysteine-specific PEGylation has been proposed as a successful… read more here.
Keywords: cysteine; hirudin variant; site; hirudin ... See more keywords