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1
Published in 2019 at "Medical Oncology"
DOI: 10.1007/s12032-019-1308-7
Abstract: Ovarian cancer is one of the most lethal gynecological cancers; owning to its late detection and chemoresistance, understanding the pathogenesis of this malignant tumor is much critical. Previous studies have reported that ubiquitin-specific peptidase 39…
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Keywords:
ubiquitin specific;
migration;
ovarian cancer;
human ovarian ... See more keywords
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0
Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep43180
Abstract: The overexpression of Mdm2 has been linked to the loss of p53 tumour suppressor activity in several human cancers. Here, we present results suggesting that ubiquitin-specific peptidase 48 (USP48), a deubiquitinase that has been linked…
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Keywords:
deubiquitinase;
specific peptidase;
deubiquitinase activity;
mdm2 ... See more keywords
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Published in 2019 at "Autophagy"
DOI: 10.1080/15548627.2018.1535291
Abstract: ABSTRACT ULK1 (unc-51 like autophagy activating kinase 1) is a core component at multiple steps of canonical macroautophagy/autophagy. The activity of ULK1 is tightly regulated by several post-translational modifications, including ubiquitination, yet the deubiquitinase (DUB)…
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Keywords:
ubiquitin specific;
complementation group;
usp1 ubiquitin;
autophagy ... See more keywords
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Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2033403
Abstract: ABSTRACT Clear cell renal cell carcinoma, the most common type of renal cancer, is associated with poor survival. Ubiquitin-specific peptidase 2 regulates the molecular mechanisms of cancer cells. However, its mechanism in clear cell renal…
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Keywords:
cell renal;
cell;
specific peptidase;
ubiquitin specific ... See more keywords
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2
Published in 2023 at "Cancer science"
DOI: 10.1111/cas.15847
Abstract: Ubiquitin-specific peptidase 24 (USP24), a member of the deubiquitinase family, plays an important role in tumor regulation. However, the role of USP24 in gastric cancer (GC) is unknown. The aim of our study was to…
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Keywords:
tumor progression;
specific peptidase;
ubiquitin specific;
glycolysis ... See more keywords
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2
Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-335
Abstract: Osteosarcoma is the heterogeneous primary malignancy of bone which is most commonly found among children and adolescents. Recent data related to treatment of osteosarcoma indicates the lack information about the progression of the disease. Osteosarcoma…
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Keywords:
replication fork;
osteosarcoma;
replication;
specific peptidase ... See more keywords
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Published in 2021 at "Archives of Medical Science"
DOI: 10.5114/aoms/132228
Abstract: 23 Introduction: Renal fibrosis is one of the common pathologies of chronic kidney disease. 24 This study aimed to investigate the function of ubiquitin specific peptidase 49 (USP49) in 25 renal fibrosis and to explore…
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Keywords:
expression;
specific peptidase;
fibrosis;
ubiquitin specific ... See more keywords
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Published in 2023 at "Japanese journal of infectious diseases"
DOI: 10.7883/yoken.jjid.2022.515
Abstract: Receptor interacting serine/threonine kinase (RIPK) 2 is associated with cellular inflammation and immune regulation. The current study explored the roles of RIPK2 in osteomyelitis and the potential upstream targets of RIPK2. S. aureus-induced osteomyelitis mouse…
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Keywords:
osteomyelitis;
specific peptidase;
ubiquitin specific;
ripk2 ubiquitination ... See more keywords