Role of Hepatocyte- and Macrophage-Specific PPARĪ³ in Hepatotoxicity Induced by Diethylhexyl Phthalate in Mice
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DOI: 10.1289/ehp9373
Abstract: Background: Phthalates may disturb metabolic homeostasis in the liver by interfering with the peroxisome proliferator-activated receptors (PPARs). However, the role of hepatic macrophages in the lipid metabolic dysregulation induced by diethylhexyl phthalate (DEHP) remains unclear.… read more here.
Keywords: phthalate; ppar; specific ppar; macrophage specific ... See more keywords