The inhibitory effect of 225 frequently-used traditional Chinese medicines for CYP3A4 metabolic enzyme by isoform-specific probe.
Sign Up to like & getrecommendations! Published in 2021 at "Fitoterapia"
DOI: 10.1016/j.fitote.2021.104858
Abstract: Traditional Chinese medicines (TCMs), have been widely used for the prevention, treatment, and cure of various diseases for thousands of years in China and Asian countries. It is usually applied either alone or in combination… read more here.
Keywords: traditional chinese; isoform specific; effect; inhibitory effect ... See more keywords
A Naturally Occurring Isoform-Specific Probe for Highly Selective and Sensitive Detection of Human Cytochrome P450 3A5.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.7b00001
Abstract: Cytochrome P450 (CYP) 3A5 characterized with polymorphic and extensive expression in multiple tissues is the most important P450 enzyme among the minor CYP3A isoforms. However, a selective and sensitive probe for CYP3A5 remains unavailable. In… read more here.
Keywords: probe; isoform specific; selective sensitive; naturally occurring ... See more keywords
Li9(d,p) reaction as a specific probe of Li10 , the paradigm of parity-inverted nuclei around the N=6 closed shell
Sign Up to like & getrecommendations! Published in 2020 at "Physical Review C"
DOI: 10.1103/physrevc.101.031305
Abstract: We show, within the framework of renormalized nuclear field theory and of the induced reaction surrogate formalism, that the highly debated $^{10}$Li structure, observed in a recent $^9$Li(d,p)$^{10}$Li one--neutron transfer experiment is consistent with or… read more here.
Keywords: reaction specific; probe li10; li9 reaction; parity ... See more keywords