Strain-Specific Propagation by an Amyloid-Beta Dodecamer
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DOI: 10.1016/j.bpj.2016.11.1962
Abstract: Soluble oligomers of the amyloid-β (Aβ) peptide have emerged as the primary neurotoxic agents in Alzheimer disease (AD). Increasing evidence implicates aggregates of Aβ to propagate towards fibrils in a strain-specific manner. Morphological differences observed… read more here.
Keywords: propagation; seed; dodecamer; specific propagation ... See more keywords