Regulation of T cell differentiation and function by ubiquitin-specific proteases.
Sign Up to like & getrecommendations! Published in 2019 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2019.103922
Abstract: T cells play critical roles in immune responses to pathogens, autoimmunity, and antitumor immunity. During the past few decades, increasing numbers of studies have demonstrated the significance of protein ubiquitination in T cell-mediated immunity. Several… read more here.
Keywords: specific proteases; cell differentiation; ubiquitin specific; differentiation function ... See more keywords
Ubiquitin-specific proteases (USPs) in leukemia: a systematic review
Sign Up to like & getrecommendations! Published in 2024 at "BMC Cancer"
DOI: 10.1186/s12885-024-12614-x
Abstract: Leukemia, a type of blood cell cancer, is categorized by the type of white blood cells affected (lymphocytes or myeloid cells) and disease progression (acute or chronic). In 2020, it ranked 15th among the most… read more here.
Keywords: systematic review; specific proteases; leukemia; proteases usps ... See more keywords
Emerging potential of ubiquitin-specific proteases and ubiquitin-specific proteases inhibitors in breast cancer treatment
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Clinical Cases"
DOI: 10.12998/wjcc.v10.i32.11690
Abstract: Breast cancer is the most frequently diagnosed cancer in women, accounting for 30% of new diagnosing female cancers. Emerging evidence suggests that ubiquitin and ubiquitination played a role in a number of breast cancer etiology… read more here.
Keywords: specific proteases; ubiquitin specific; breast cancer; cancer treatment ... See more keywords
Role of ubiquitin specific proteases in the immune microenvironment of prostate cancer: A new direction
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.955718
Abstract: Regulation of ubiquitination is associated with multiple processes of tumorigenesis and development, including regulation of the tumor immune microenvironment. Deubiquitinating enzymes (DUBs) can remove ubiquitin chains from substrates, thereby stabilizing target proteins and altering and… read more here.
Keywords: prostate cancer; specific proteases; immune microenvironment; ubiquitin specific ... See more keywords
An insight into the roles of ubiquitin-specific proteases in plants: development and growth, morphogenesis, and stress response
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2024.1396634
Abstract: Ubiquitination is a highly conserved and dynamic post-translational modification in which protein substrates are modified by ubiquitin to influence their activity, localization, or stability. Deubiquitination enzymes (DUBs) counter ubiquitin signaling by removing ubiquitin from the… read more here.
Keywords: development growth; specific proteases; morphogenesis stress; ubiquitin specific ... See more keywords
Deubiquitinating Enzymes Ubiquitin-Specific Proteases 7 and 10 Regulate TAU Aggregation
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms262211062
Abstract: Accumulation of the microtubule-associated protein TAU into inclusions is a hallmark of tauopathies including Alzheimer’s disease (AD), potentially driven by impaired protein degradation and dysregulated ubiquitination. To explore the role of deubiquitinating enzymes (DUBs), we… read more here.
Keywords: tau aggregation; usp7 usp10; specific proteases; tau ... See more keywords