Articles with "specific proximity" as a keyword



Abstract 3885: A ubiquitin-specific proximity labeling method to study drug-induced ubiquitylation

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.am2024-3885

Abstract: Targeted protein degradation is a promising therapeutic paradigm that offers new ways to disrupt protein functions. Currently, most studies that characterize the pharmacological effects of protein degraders utilize target-specific assays and global proteomics. However, information… read more here.

Keywords: labeling method; specific proximity; ubiquitylation; proximity labeling ... See more keywords