Characterization of a novel group I F-specific RNA bacteriophage isolated from human stool.
Sign Up to like & getrecommendations! Published in 2021 at "Archives of microbiology"
DOI: 10.1007/s00203-021-02402-7
Abstract: A novel F-specific RNA bacteriophage (FRNAPH) YM1, affiliating to genogroup I (GI) of Levivirus, is isolated for the first time from human stool samples using double-layer agar plates with the Escherichia coli ATCC700891 as the… read more here.
Keywords: specific rna; novel; human stool; rna bacteriophage ... See more keywords
Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical biology"
DOI: 10.1021/acschembio.1c00732
Abstract: Methylation of specific nucleotides is integral for ribosomal biogenesis and also serves as a common mechanism to confer antibiotic resistance by pathogenic bacteria. Here, by determining the high-resolution structure of the 30S-KsgA complex by cryo-electron… read more here.
Keywords: specific rna; rna targeting; mechanism specific; decoding mechanism ... See more keywords
Allele-Specific RNA Knockdown with a Biologically Stable and Catalytically Efficient XNAzyme.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.0c11353
Abstract: Therapeutic targeting of allele-specific single nucleotide mutations in RNA is a major challenge in biology and medicine. Herein, we describe the utility of the XNAzyme X10-23 to knock down allele-specific mRNA sequences in cells. We… read more here.
Keywords: specific rna; xnazyme; knockdown biologically; rna knockdown ... See more keywords
Long non-coding and coding RNA profiling using strand-specific RNA-seq in human hypertrophic cardiomyopathy
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Data"
DOI: 10.1038/s41597-019-0094-6
Abstract: Hypertrophic cardiomyopathy (HCM) represents one of the most common heritable heart diseases. However, the signalling pathways and regulatory networks underlying the pathogenesis of HCM remain largely unknown. Here, we present a strand-specific RNA-seq dataset for… read more here.
Keywords: specific rna; strand specific; rna; hypertrophic cardiomyopathy ... See more keywords
Eukaryote specific RNA and protein features facilitate assembly and catalysis of H/ACA snoRNPs
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab177
Abstract: Abstract H/ACA Box ribonucleoprotein complexes (RNPs) play a major role in modification of rRNA and snRNA, catalyzing the sequence specific pseudouridylation in eukaryotes and archaea. This enzymatic reaction takes place on a substrate RNA recruited… read more here.
Keywords: specific rna; eukaryote specific; snornps; aca ... See more keywords
F-Specific RNA Bacteriophages Model the Behavior of Human Noroviruses during Purification of Oysters: the Main Mechanism Is Probably Inactivation Rather than Release
Sign Up to like & getrecommendations! Published in 2020 at "Applied and Environmental Microbiology"
DOI: 10.1128/aem.00526-20
Abstract: This study provides new data about the behavior of viruses in oysters under purification processes and about their elimination mechanism. First, a high correlation has been observed between F-specific RNA bacteriophages of subgroup II (FRNAPH-II)… read more here.
Keywords: purification; frnaph; rna bacteriophages; specific rna ... See more keywords
AR-V7 detection by a novel junction-specific RNA in situ hybridization (RISH) test.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.6_suppl.191
Abstract: 191Background: Previous studies have reported an association between blood-based detection of androgen receptor splice variant-7 (AR-V7) and resistance to abiraterone/enzalutamide in men with metastatic castration-resistant prostate cancer (mCRPC). Further characterization of AR-V7 and its clinical… read more here.
Keywords: specific rna; detection; novel junction; rna situ ... See more keywords
Occurrence and reduction of F-specific RNA bacteriophage genotypes as indicators of human norovirus at a wastewater treatment plant.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of water and health"
DOI: 10.2166/wh.2018.367
Abstract: F-specific RNA bacteriophages (FRNAPHs) have been suggested as good indicators of the presence of human enteric viruses in water treatment facilities. The occurrence and reduction of norovirus (NoV) and FRNAPH genotypes in wastewater treatment plants… read more here.
Keywords: specific rna; treatment; occurrence reduction; wastewater treatment ... See more keywords
The Identification of MATE Antisense Transcripts in Soybean Using Strand-Specific RNA-Seq Datasets
Sign Up to like & getrecommendations! Published in 2022 at "Genes"
DOI: 10.3390/genes13020228
Abstract: Natural antisense transcripts (NATs) have been generally reported as negative regulators of their sense counterparts. Multidrug and toxic compound extrusion (MATE) proteins mediate the transport of various substrates. Although MATEs have been identified genome-wide in… read more here.
Keywords: antisense transcripts; specific rna; mate antisense; mate ... See more keywords
Reciprocal antagonistic regulation of N-myc mRNA by miR-17 and the neuronal-specific RNA-binding protein HuD
Sign Up to like & getrecommendations! Published in 2017 at "Oncology Reports"
DOI: 10.3892/or.2017.5664
Abstract: Neuroblastoma is a childhood cancer originating from embryonic neural crest cells. Amplification of the proto-oncogene N-myc, seen in ~30% of neuroblastoma tumors, is a marker for poor prognosis. Recently discovered small regulatory RNAs, microRNAs (miRNAs),… read more here.
Keywords: specific rna; neuronal specific; myc mrna; myc amplified ... See more keywords