The context-specific roles of urea cycle enzymes in tumorigenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular cell"
DOI: 10.1016/j.molcel.2021.08.005
Abstract: The expression of the urea cycle (UC) proteins is dysregulated in multiple cancers, providing metabolic benefits to tumor survival, proliferation, and growth. Here, we review the main changes described in the expression of UC enzymes… read more here.
Keywords: specific roles; cycle enzymes; urea cycle; context specific ... See more keywords
Stage-specific roles of microbial dysbiosis and metabolic disorders in rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-222871
Abstract: Objective Rheumatoid arthritis (RA) is a progressive disease including four stages, where gut microbiome is associated with pathogenesis. We aimed to investigate stage-specific roles of microbial dysbiosis and metabolic disorders in RA. Methods We investigated… read more here.
Keywords: microbial dysbiosis; stage specific; specific roles; stage ... See more keywords
Autophagy and Its Lineage-Specific Roles in the Hematopoietic System
Sign Up to like & getrecommendations! Published in 2023 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2023/8257217
Abstract: Autophagy is a dynamic process that regulates the selective and nonselective degradation of cytoplasmic components, such as damaged organelles and protein aggregates inside lysosomes to maintain tissue homeostasis. Different types of autophagy including macroautophagy, microautophagy,… read more here.
Keywords: specific roles; autophagy lineage; lineage specific; hematopoietic system ... See more keywords
CXCL12 Has Niche-Specific Roles in Leukemia Stem Cell Function.
Sign Up to like & getrecommendations! Published in 2019 at "Cancer discovery"
DOI: 10.1158/2159-8290.cd-rw2019-044
Abstract: MSC-expressed CXCL12 promotes LSC quiescence and promotes BCR-ABL inhibitor resistance. read more here.
Keywords: niche specific; specific roles; cxcl12 niche; roles leukemia ... See more keywords
Editorial: Identifying the isoform-specific roles of RAS paralogs in health and disease
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2023.1199356
Abstract: Stem Cell Biology and Regenerative Medicine Research Group, Institute of Biotechnology, Ferdowsi University of Mashhad, Mashhad, Iran, Institute of Biochemistry and Molecular Biology II, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Düsseldorf,… read more here.
Keywords: identifying isoform; specific roles; editorial identifying; roles ras ... See more keywords
The Conserved and Specific Roles of the LUX ARRHYTHMO in Circadian Clock and Nodulation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23073473
Abstract: LUX ARRHYTHMO (LUX) plays a key role in circadian rhythms and flowering. Here, we identified the MtLUX gene which is the putative ortholog of LUX in Medicago truncatula. The roles of MtLUX, in both the… read more here.
Keywords: conserved specific; specific roles; nodulation; lux arrhythmo ... See more keywords