Engineering of Specific Single-Module Nonribosomal Peptide Synthetases of the RXP Type for the Production of Defined Peptides
Sign Up to like & getrecommendations! Published in 2022 at "ACS Synthetic Biology"
DOI: 10.1021/acssynbio.2c00472
Abstract: Rhabdopeptide/xenortide-like peptide (RXP) nonribosomal peptide synthetases (NRPSs) derived from entomophathogenic Xenorhabdus and Photorhabdus bacteria often produce libraries of different peptides varying in amino acid composition, number and degree of methylation, which mainly is a result… read more here.
Keywords: specific single; engineering specific; single module; peptide synthetases ... See more keywords
Combined effects of scanning ultrasound and a tau-specific single chain antibody in a tau transgenic mouse model
Sign Up to like & getrecommendations! Published in 2017 at "Brain"
DOI: 10.1093/brain/awx052
Abstract: One of the greatest challenges for the treatment of neurodegenerative disease is crossing the blood-brain barrier. Nisbet et al. demonstrate that non-invasive scanning ultrasound increases the delivery of tau-specific single-chain antibody fragments across the blood-brain… read more here.
Keywords: tau; chain antibody; tau specific; scanning ultrasound ... See more keywords