A cysteine-specific solubilizing tag strategy enables efficient chemical protein synthesis of difficult targets
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DOI: 10.1039/d3sc06032b
Abstract: We developed a new cysteine-specific solubilizing tag strategy via a cysteine-conjugated succinimide. This solubilizing tag remains stable under common native chemical ligation conditions and can be efficiently removed with palladium-based catalysts. Utilizing this approach, we… read more here.
Keywords: cysteine specific; specific solubilizing; tag strategy; solubilizing tag ... See more keywords