Adoptive Induced Antigen-Specific Treg Cells Reverse Inflammation in Collagen-Induced Arthritis Mouse Model
Sign Up to like & getrecommendations! Published in 2017 at "Inflammation"
DOI: 10.1007/s10753-017-0704-4
Abstract: Rheumatoid arthritis (RA) is a systemic autoimmune disease that may cause bone damage and worsening disability. Manipulating antigen-specific Treg cells is a promising approach to treat autoimmune disease since the immune suppressive function of Treg… read more here.
Keywords: treg cells; antigen specific; specific treg; arthritis ... See more keywords
Isolation and enrichment of mouse insulin-specific CD4+ T regulatory cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of immunological methods"
DOI: 10.1016/j.jim.2019.04.011
Abstract: Polyclonal T regulatory cells (Treg - CD4+CD25+CD127lowFoxp3+) are used in several protocols for the treatment of type 1 diabetes (T1D), multiple sclerosis and graft-versus host disease in clinical trials. However, general opinion is that autoantigen-specific… read more here.
Keywords: insulin; insulin specific; regulatory cells; specific treg ... See more keywords