Abstract 584: Doppel, an exosome mediated biomarker specific to tumor endothelial cells
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-584
Abstract: The difficulty of finding a biomarker that is both specific and ubiquitous in cancer presents a barrier to targeted drug delivery. Some tumor-associated antigens are also found in normal tissue and contribute to “on-target toxicities”.… read more here.
Keywords: endothelial cells; biomarker specific; tumor endothelial; specific tumor ... See more keywords
Appendiceal Cancer Patient-Specific Tumor Organoid Model for Predicting Chemotherapy Efficacy Prior to Initiation of Treatment: A Feasibility Study
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DOI: 10.1245/s10434-018-7008-2
Abstract: IntroductionWe have hypothesized that biofabrication of appendiceal tumor organoids allows for a more personalized clinical approach and facilitates research in a rare disease.MethodsAppendiceal cancer specimens obtained during cytoreduction with hyperthermic intraperitoneal chemotherapy procedures (CRS/HIPEC) were… read more here.
Keywords: tumor; patient specific; tumor organoids; cancer ... See more keywords
BRCA1-Dependent Transcriptional Regulation: Implication in Tissue-Specific Tumor Suppression
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DOI: 10.3390/cancers10120513
Abstract: Germ-line mutations in breast cancer susceptibility gene 1 (BRCA1) predominantly predispose women to breast and ovarian cancers. BRCA1 is best known for its functions in maintenance of genomic integrity including repairing DNA double-strand breaks through… read more here.
Keywords: transcriptional regulation; specific tumor; tissue specific; regulation ... See more keywords