Structural Insights into Substrate Specificity of Acyltransferases from Salinomycin Polyketide Synthase.
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DOI: 10.1021/acs.biochem.9b00305
Abstract: Salinomycin with antibacterial and anticoccidial activities is a commercial polyether polyketide widely used in animal husbandry as a food additive. Malonyl-CoA (MCoA), methylmalonyl-CoA (MMCoA) and ethylmalonyl-CoA (EMCoA) are used as extension units in its biosynthesis.… read more here.
Keywords: structural insights; polyketide synthase; specificity acyltransferases; insights substrate ... See more keywords