Not all cancers are created equal: Tissue specificity in cancer genes and pathways.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2020.01.005
Abstract: Tumors arise through waves of genetic alterations and clonal expansion that allow tumor cells to acquire cancer hallmarks, such as genome instability and immune evasion. Recent genomic analyses showed that the vast majority of cancer… read more here.
Keywords: tissue specificity; tissue; cancer; cell ... See more keywords
Tissue-specificity in cancer: The rule, not the exception
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aaw3472
Abstract: Cancer driver genes exhibit remarkable tissue-specificity We are in the midst of a renaissance in cancer genetics. Over the past several decades, candidate-based targeted sequencing efforts provided a steady stream of information on the genetic… read more here.
Keywords: cancer rule; tissue specificity; tissue; cancer ... See more keywords