Insights into the evolution of enzymatic specificity and catalysis: From Asgard archaea to human adenylate kinases
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DOI: 10.1126/sciadv.abm4089
Abstract: Enzymatic catalysis is critically dependent on selectivity, active site architecture, and dynamics. To contribute insights into the interplay of these properties, we established an approach with NMR, crystallography, and MD simulations focused on the ubiquitous… read more here.
Keywords: catalysis; insights evolution; evolution enzymatic; enzymatic specificity ... See more keywords