Multi-Substrate Specificity and the Evolutionary Basis for Interdependence in tRNA Editing and Methylation Enzymes
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DOI: 10.3389/fgene.2019.00104
Abstract: Among tRNA modification enzymes there is a correlation between specificity for multiple tRNA substrates and heteromultimerization. In general, enzymes that modify a conserved residue in different tRNA sequences adopt a heterodimeric structure. Presumably, such changes… read more here.
Keywords: trna editing; specificity evolutionary; multi substrate; trna ... See more keywords