131 I-Labeled Multifunctional Polyphosphazene Nanospheres for SPECT Imaging-Guided Radiotherapy of Tumors.
Sign Up to like & getrecommendations! Published in 2019 at "Advanced healthcare materials"
DOI: 10.1002/adhm.201901299
Abstract: Design of theranostic nanoplatforms represents a major topic for current nanomedicine. Here, the preparation of multifunctional poly(cyclotriphosphazene-co-polyethylenimine) nanospheres (PNSs) labeled with radionuclide 131 I for single photon emission computed tomography (SPECT) imaging-guided radiotherapy of tumors… read more here.
Keywords: hpao 131; guided radiotherapy; spect imaging; radiotherapy ... See more keywords
99mTc-HMPAO SPECT imaging reveals brain hypoperfusion during status epilepticus.
Sign Up to like & getrecommendations! Published in 2021 at "Metabolic brain disease"
DOI: 10.1007/s11011-021-00843-z
Abstract: Status epilepticus (SE) is a clinical emergency with high mortality. SE can trigger neuronal death or injury and alteration of neuronal networks resulting in long-term cognitive decline or epilepsy. Among the multiple factors contributing to… read more here.
Keywords: hmpao spect; perfusion; spect imaging; status epilepticus ... See more keywords
Quantitative SPECT/CT imaging for medication-related osteonecrosis of the jaw: a preliminary study using volume-based parameters, comparison with chronic osteomyelitis
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Nuclear Medicine"
DOI: 10.1007/s12149-019-01390-5
Abstract: To investigate the quantitative SPECT/CT imaging for medication-related osteonecrosis of the jaw (MRONJ) using volume-based parameters. Thirteen patients with mandibular lesions (nine MRONJ and four chronic osteomyelitis) underwent SPECT/CT acquisition at 4 h after injection… read more here.
Keywords: chronic osteomyelitis; quantitative spect; volume; spect imaging ... See more keywords
Automatic Striatal ROI Delineation for Semi-quantitative Analysis of 99mTc-TRODAT-1 Brain SPECT Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Medical and Biological Engineering"
DOI: 10.1007/s40846-020-00530-x
Abstract: Single-photon emission computed tomography (SPECT) imaging, a relatively inexpensive nuclear imaging technique, has been used as a diagnostic tool for Parkinson’s disease (PD). The tracer 99mTc-TRODAT-1 is commonly used in Taiwan, where the imaging cost… read more here.
Keywords: trodat; spect imaging; roi delineation; 99mtc trodat ... See more keywords
[P003] Method using radiochromic films to measure the CT dose of female breast during SPECT/CT imaging
Sign Up to like & getrecommendations! Published in 2018 at "Physica Medica"
DOI: 10.1016/j.ejmp.2018.06.336
Abstract: Objectives The objective of this work was to test the feasibility of in vivo dosimetry method to be used for the assessment of entrance surface dose (ESD) on female breast from the computed tomography (CT)… read more here.
Keywords: part; spect; spect imaging; method ... See more keywords
In vivo SPECT-CT imaging and characterization of technetium-99m-labeled bevacizumab-loaded human serum albumin pegylated nanoparticles
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101809
Abstract: Abstract The aim of this work was to study the biodistribution of bevacizumab-loaded HSA nanoparticles (NP-Ab) cross-linked with PEG35000 by SPECT/CT in vivo imaging. For this purpose, NP-Abs were prepared by a desolvation process, coated… read more here.
Keywords: bevacizumab loaded; spect imaging; vivo spect; imaging characterization ... See more keywords
[123I]Ioflupane imaging in Caucasians and non-Caucasians: Are there any differences?
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Neurological Sciences"
DOI: 10.1016/j.jns.2018.10.001
Abstract: PURPOSE OF THE REPORT To compare diagnostic performance of [123I]ioflupane SPECT imaging in different racial groups. In previous registration trials of [123I]ioflupane, 99% of the subjects enrolled were Caucasians. MATERIALS AND METHODS A multicenter retrospective… read more here.
Keywords: spect imaging; non caucasians; ioflupane spect; ioflupane ... See more keywords
Development of [99mTc]TcO-ABX474: Design, Synthesis, and Biological Evaluation of PSMA-Binding Technetium-99m Radioligands for SPECT Imaging of Prostate Cancer
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.4c02767
Abstract: A current global limitation to the timely and equitable patient access to PSMA-based therapies for prostate cancer (PCa) is the insufficient PET capacity for pretreatment imaging. However, the extensive global availability of SPECT cameras renders… read more here.
Keywords: prostate cancer; spect imaging; psma; radioligands spect ... See more keywords
Noninvasive Imaging of Tumor PD-L1 Expression Using [99mTc]Tc-Labeled KN035 with SPECT/CT.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00874
Abstract: Programmed cell death protein-1/ligand-1 (PD-1/PD-L1) checkpoint blockade is a major breakthrough in cancer therapy, but identifying patients likely to benefit from this therapy remains challenging. Immunohistochemistry is not informative about PD-L1 expression heterogeneity because of… read more here.
Keywords: hynic kn035; spect imaging; expression; 99mtc hynic ... See more keywords
Safety, Biodistribution, and Dosimetry Study of Meplazumab, a Potential COVID-19 Therapeutic Drug, with 131I-Labeling and SPECT Imaging
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00954
Abstract: Coronavirus disease 2019 (COVID-19) is a serious threat to public health and is in urgent need of specific drugs. Meplazumab, a humanized monoclonal antibody targeting CD147, was confirmed to competitively block the binding between the… read more here.
Keywords: spect imaging; biodistribution; 131i meplazumab; drug ... See more keywords
SPECT/CT Imaging of 111Ag for the Preclinical Evaluation of Silver-Based Antimicrobial Nanomedicines.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c03609
Abstract: With the growing interest in developing silver-based antimicrobials, there is a need to better understand the behavior of silver within biological systems. To address this, we showed that single-photon emission computed tomography (SPECT) is a… read more here.
Keywords: preclinical evaluation; spect imaging; silver; 111ag preclinical ... See more keywords