EMBER multidimensional spectral microscopy enables quantitative determination of disease- and cell-specific amyloid strains
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DOI: 10.1073/pnas.2300769120
Abstract: Significance In neurodegenerative diseases, proteins fold into amyloid structures with distinct conformations (strains). There is a need to rapidly identify these amyloid conformations in situ. Here, we use machine learning on the full information available… read more here.
Keywords: spectral microscopy; multidimensional spectral; disease; microscopy ... See more keywords