Emerging Computational Methods in Mass Spectrometry Imaging
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202203339
Abstract: Mass spectrometry imaging (MSI) is a powerful analytical technique that generates maps of hundreds of molecules in biological samples with high sensitivity and molecular specificity. Advanced MSI platforms with capability of high‐spatial resolution and high‐throughput… read more here.
Keywords: mass spectrometry; computational methods; emerging computational; spectrometry imaging ... See more keywords
Mass Spectrometry Imaging of 3D Tissue Models
Sign Up to like & getrecommendations! Published in 2018 at "PROTEOMICS"
DOI: 10.1002/pmic.201700462
Abstract: A 3D cell culture is an artificially created environment in which cells are permitted to grow/interact with their surroundings in all three dimensions. Derived from 3D cell culture, organoids are generally small‐scale constructs of cells… read more here.
Keywords: methodology; mass spectrometry; tissue models; drug ... See more keywords
Surface‐sampling mass spectrometry and imaging: Direct analysis of bacterial species
Sign Up to like & getrecommendations! Published in 2020 at "Surface and Interface Analysis"
DOI: 10.1002/sia.6907
Abstract: Surface‐sampling mass spectrometry and imaging techniques offer the opportunity to directly interrogate a wide range of surfaces. Ambient techniques have become popular as samples can be analysed at room conditions with little to no sample… read more here.
Keywords: spectrometry imaging; analysis; surface sampling; mass spectrometry ... See more keywords
High-Spatial Resolution Mass Spectrometry Imaging: Toward Single Cell Metabolomics in Plant Tissues.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical record"
DOI: 10.1002/tcr.201700027
Abstract: Mass spectrometry imaging (MSI) is a powerful tool that has advanced our understanding of complex biological processes by enabling unprecedented details of metabolic biology to be uncovered. Through the use of high-spatial resolution MSI, metabolite… read more here.
Keywords: resolution; high spatial; mass spectrometry; spatial resolution ... See more keywords
MALDI Mass Spectrometry Imaging of Lipids on Free-Floating Brain Sections and Immunohistochemically Colocalized Markers of Neurodegeneration.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2030-4_16
Abstract: In mass spectrometry imaging (MSI), the essential steps in sample preparation include collection and storage. The most widely used preservation procedure for MSI consists in freezing samples and storing them at temperatures below -80 °C. On… read more here.
Keywords: floating brain; mass spectrometry; spectrometry imaging; brain sections ... See more keywords
Mass Spectrometry Imaging of Biological Tissues by Laser Desorption Ionization from Silicon Nanopost Arrays.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-2030-4_6
Abstract: Mass spectrometry imaging (MSI) plays an expanding role in the label-free spatial mapping of hundreds of molecules simultaneously. Currently, matrix-assisted laser desorption ionization (MALDI) is among the most widely adopted MSI techniques. However, matrix application… read more here.
Keywords: laser desorption; mass spectrometry; ionization; spectrometry imaging ... See more keywords
Mass Spectrometry Imaging of Metabolites.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7592-1_26
Abstract: Mass spectrometry imaging (MSI) is a technique which is gaining increasing interest in biomedical research due to its capacity to visualize molecules in tissues. First applied to the field of clinical proteomics, its potential for… read more here.
Keywords: spectrometry imaging; imaging metabolites; biology; mass spectrometry ... See more keywords
Round robin study of formalin-fixed paraffin-embedded tissues in mass spectrometry imaging
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1216-2
Abstract: AbstractMass spectrometry imaging (MSI) has provided many results with translational character, which still have to be proven robust in large patient cohorts and across different centers. Although formalin-fixed paraffin-embedded (FFPE) specimens are most common in… read more here.
Keywords: fixed paraffin; msi; paraffin embedded; study ... See more keywords
MALDI-TOF mass spectrometry imaging for N-glycans on FFPE tissue sections of mouse NASH liver through Sialic acid Benzylamidation.
Sign Up to like & getrecommendations! Published in 2021 at "Glycoconjugate journal"
DOI: 10.1007/s10719-021-09984-w
Abstract: Glycans play an important physiological role and are drawing attention as biomarkers that capture pathophysiological changes. Glycans can be detected by mass spectrometry, but recently matrix-assisted laser desorption/ionization- mass spectrometry imaging (MALDI-MSI) has enabled the… read more here.
Keywords: mass spectrometry; benzylamidation; mass; spectrometry imaging ... See more keywords
massPix: an R package for annotation and interpretation of mass spectrometry imaging data for lipidomics
Sign Up to like & getrecommendations! Published in 2017 at "Metabolomics"
DOI: 10.1007/s11306-017-1252-5
Abstract: IntroductionMass spectrometry imaging (MSI) experiments result in complex multi-dimensional datasets, which require specialist data analysis tools.ObjectivesWe have developed massPix—an R package for analysing and interpreting data from MSI of lipids in tissue.MethodsmassPix produces single ion… read more here.
Keywords: spectrometry imaging; masspix package; mass; interpretation ... See more keywords
Ambient ionization mass spectrometry imaging for disease diagnosis: Excitements and challenges
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Biosciences"
DOI: 10.1007/s12038-018-9785-y
Abstract: Tissue analysis in histology is extremely important and also considered to be a gold standard to diagnose and prognosticate several diseases including cancer. Intraoperative evaluation of surgical margin of tumor also relies on frozen section… read more here.
Keywords: mass spectrometry; ambient ionization; histopathology; ionization mass ... See more keywords