Design, synthesis and spectroscopic and crystallographic characterisation of novel functionalized pyrazole derivatives: biological evaluation for their cytotoxic, angiogenic and antioxidant activities
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DOI: 10.1007/s11164-018-3445-6
Abstract: The current study presents the synthesis of functionalized pyrazoles (18–29) through 3 + 2 annulation reaction of ethyl 2-(arylidene)-3-oxobutanoates (8–13) with phenylhydrazine hydrochlorides (14–17) in acetic acid under reflux conditions. Structures of the synthesized new compounds were… read more here.
Keywords: novel; design synthesis; crystallographic characterisation; spectroscopic crystallographic ... See more keywords