Orally Efficacious Broad-Spectrum Allosteric Inhibitor of Paramyxovirus Polymerase
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DOI: 10.1038/s41564-020-0752-7
Abstract: Paramyxoviruses such as human parainfluenza virus type-3 (HPIV3) and measles virus (MeV) are a substantial health threat. In a high-throughput screen for inhibitors of HPIV3 (a major cause of acute respiratory infection), we identified GHP-88309—a… read more here.
Keywords: spectrum allosteric; hpiv3; polymerase; viral polymerase ... See more keywords