Crossiellidines A-F, Unprecedented Pyrazine-Alkylguanidine Metabolites with Broad-Spectrum Antibacterial Activity from Crossiella sp.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.3c01088
Abstract: Crosiellidines are intriguing pyrazine-alkylguanidine metabolites isolated from the minor actinomycete genus Crossiella. Their structures present an unprecedented 2-methoxy-3,5,6-trialkyl pyrazine scaffold and uncommon guanidine prenylations, including an exotic O-prenylated N-hydroxyguanidine moiety. The novel substitution pattern of… read more here.
Keywords: alkylguanidine metabolites; antibacterial activity; pyrazine alkylguanidine; spectrum antibacterial ... See more keywords
Tailored Ag-Cu-Mg multielemental nanoparticles for wide-spectrum antibacterial coating.
Sign Up to like & getrecommendations! Published in 2019 at "Nanoscale"
DOI: 10.1039/c8nr08375d
Abstract: Bactericidal nanoparticle coatings are very promising for hindering the indirect transmission of pathogens through cross-contaminated surfaces. The challenge, limiting their employment in nosocomial environments, is the ability of tailoring the coating's physicochemical properties, namely, composition,… read more here.
Keywords: wide spectrum; antibacterial coating; tailored multielemental; multielemental nanoparticles ... See more keywords
Cellular membrane-targeting ruthenium complexes as efficient photosensitizers for broad-spectrum antibacterial activity.
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DOI: 10.1039/d3dt01001e
Abstract: A ruthenium complex [Ru(phen)2(phen-5-amine)-C14] (Ru-C14) with broad-spectrum antibacterial activity was designed and synthesized; positively charged Ru-C14 could target bacteria via electrostatic interactions and showed high binding effectiveness to cell membranes. In addition, Ru-C14 could act… read more here.
Keywords: c14; antibacterial activity; membrane targeting; spectrum antibacterial ... See more keywords
A wide spectrum of antibacterial activity of secondary metabolites from Bacillus amyloliquefaciens ELI149
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DOI: 10.14393/bj-v35n6a2019-42660
Abstract: A highly potent secondary metabolites-producing Bacillus strain was isolated from Mexican soil (Puebla State), together with other fifty strains. The fifty-one strains were subjected for metabolites extraction and evaluated as antibacterial against several bacteria. The… read more here.
Keywords: antibacterial activity; spectrum antibacterial; bacillus amyloliquefaciens; wide spectrum ... See more keywords
Narrow-Spectrum Antibacterial Agents—Benefits and Challenges
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DOI: 10.3390/antibiotics9070418
Abstract: The number of antibacterial agents in clinical and preclinical development possessing activity against a narrow spectrum of bacterial pathogens is increasing, with many of them being nontraditional products. The key value proposition hinges on sparing… read more here.
Keywords: narrow spectrum; benefits challenges; antibacterial agents; agents benefits ... See more keywords
Environmentally Friendly and Broad–Spectrum Antibacterial Poly(hexamethylene guanidine)–Modified Polypropylene and Its Antifouling Application
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DOI: 10.3390/polym15061521
Abstract: Biological fouling is one of the main reasons that limits the application of traditional polypropylene (PP) fishing nets in aquaculture. Here, a new environmentally friendly and broad–spectrum antibacterial agent called cationic poly(hexamethylene guanidine) (PHMG) was… read more here.
Keywords: phmg; friendly broad; environmentally friendly; spectrum antibacterial ... See more keywords