Articles with "spectrum inhibitors" as a keyword



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N-Aryl Mercaptopropionamides as Broad-Spectrum Inhibitors of Metallo-β-Lactamases.

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Published in 2022 at "Journal of medicinal chemistry"

DOI: 10.1021/acs.jmedchem.1c01755

Abstract: Drug-resistant pathogens pose a global challenge to public health as they cause diseases that are extremely difficult to cure. Metallo-β-lactamases (MBLs) are a diverse set of zinc-containing enzymes that catalyze the hydrolysis of β-lactam drugs,… read more here.

Keywords: aryl mercaptopropionamides; inhibitors metallo; spectrum inhibitors; mercaptopropionamides broad ... See more keywords