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Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01755
Abstract: Drug-resistant pathogens pose a global challenge to public health as they cause diseases that are extremely difficult to cure. Metallo-β-lactamases (MBLs) are a diverse set of zinc-containing enzymes that catalyze the hydrolysis of β-lactam drugs,…
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Keywords:
aryl mercaptopropionamides;
inhibitors metallo;
spectrum inhibitors;
mercaptopropionamides broad ... See more keywords