Interplay mechanisms between progesterone and endocannabinoid receptors in regulating bull sperm capacitation and acrosome reaction
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30753
Abstract: After ejaculation, sperm show a limited capacity for transcription and translation. In the oviduct, most of the signalling in sperm is nongenomic and is mediated through membrane receptors. Studies have shown that the cation channel… read more here.
Keywords: interplay; capacitation acrosome; acrosome reaction; sperm capacitation ... See more keywords
Testis‐specific isoform of angiotensin‐converting enzyme (tACE) is involved in the regulation of bovine sperm capacitation
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22790
Abstract: We hypothesized that the testis‐specific isoform of angiotensin‐converting enzyme (tACE) is released during bovine sperm capacitation, and its peptidase activity is required for capacitation. Specific objectives of this study were to (i) develop an anti‐tACE… read more here.
Keywords: bovine sperm; sperm capacitation; tace; specific isoform ... See more keywords
Iberiotoxin and clofilium regulate hyperactivation, acrosome reaction, and ion homeostasis synergistically during human sperm capacitation
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23671
Abstract: Potassium channels play essential roles in the regulation of male fertility. However, potassium channels mediating K+ currents in human sperm (IKSper) remain controversial. Besides SLO3, the SLO1 potassium channel is a potential candidate for human… read more here.
Keywords: capacitation; hyperactivation; clofilium; acrosome reaction ... See more keywords
A membrane-associated adenylate cyclase modulates lactate dehydrogenase and creatine kinase activities required for bull sperm capacitation induced by hyaluronic acid.
Sign Up to like & getrecommendations! Published in 2017 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2017.02.004
Abstract: Hyaluronic acid, as well as heparin, is a glycosaminoglycan present in the female genital tract of cattle. The aim of this study was to evaluate oxidative metabolism and intracellular signals mediated by a membrane-associated adenylate… read more here.
Keywords: sperm capacitation; capacitation; bull sperm; hyaluronic acid ... See more keywords
Evaluation of boar and bull sperm capacitation and the acrosome reaction using flow cytometry.
Sign Up to like & getrecommendations! Published in 2021 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2021.106846
Abstract: Flow cytometry can be used to evaluate many sperm attributes and Dr. Duane Garner was influential in developing assays to understand sperm physiology and function. We review some of Dr. Garner's work and describe experiments… read more here.
Keywords: sperm capacitation; capacitation; philosophy; physiology ... See more keywords
C-type natriuretic peptide regulates sperm capacitation by the cGMP/PKG signalling pathway via Ca2+ influx and tyrosine phosphorylation.
Sign Up to like & getrecommendations! Published in 2019 at "Reproductive biomedicine online"
DOI: 10.1016/j.rbmo.2018.11.025
Abstract: RESEARCH QUESTION What is the effect of C-type natriuretic peptide (CNP) on human sperm capacitation in vitro and what is the mechanism of this effect? DESIGN CNP/NPR-B expression in the female rat genital tract was… read more here.
Keywords: sperm capacitation; cnp; cgmp; pkg ... See more keywords
Biological effects of polyphenol-rich extract and fractions from an oenological oak-derived tannin on in vitro swine sperm capacitation and fertilizing ability.
Sign Up to like & getrecommendations! Published in 2018 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2017.12.015
Abstract: Although excessive ROS levels induce sperm damage, sperm capacitation is an oxidative event that requires low amounts of ROS. As the antioxidant activity of the ethanol extract (TRE) of a commercial oenological tannin (Quercus robur… read more here.
Keywords: sperm capacitation; fertilizing ability; tre fractions; capacitation ... See more keywords
GPx6 is involved in the in vitro induced capacitation and acrosome reaction in porcine sperm.
Sign Up to like & getrecommendations! Published in 2020 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2020.06.020
Abstract: Glutathione peroxidases (GPxs) are regarded as important protectors against oxidative stress. Some members of this protein family were reported to play key roles in protecting sperm against oxidative stress. Whether GPx6 a member of the… read more here.
Keywords: sperm capacitation; sperm gpx6; capacitation; gpx6 antibody ... See more keywords
Compartmentalization of the proteasome-interacting proteins during sperm capacitation
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-49024-0
Abstract: Ubiquitination is a stable, reversible posttranslational modification of target proteins by covalent ligation of the small chaperone protein ubiquitin. Most commonly ubiquitination targets proteins for degradation/recycling by the 26S proteasome in a well-characterized enzymatic cascade.… read more here.
Keywords: sperm capacitation; proteasome interacting; capacitation; interacting proteins ... See more keywords
Acrosomal alkalinization occurs during human sperm capacitation.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular human reproduction"
DOI: 10.1093/molehr/gaac005
Abstract: Mammalian sperm capacitation is a prerequisite for successful fertilization. Capacitation involves biochemical and physiological modifications of sperm as they travel through the female reproductive tract. These modifications prepare the sperm to undergo the acrosome reaction… read more here.
Keywords: capacitation; acrosomal alkalinization; sperm capacitation; pha ... See more keywords
High throughput small RNA and transcriptome sequencing reveal capacitation-related microRNAs and mRNA in boar sperm
Sign Up to like & getrecommendations! Published in 2018 at "BMC Genomics"
DOI: 10.1186/s12864-018-5132-9
Abstract: BackgroundCapacitation, a prerequisite for oocyte fertilization, is a complex process involving series of structural and functional changes in sperms such as membrane modifications, modulation of enzyme activities, and protein phosphorylation. In order to penetrate and… read more here.
Keywords: sperm capacitation; capacitation related; capacitation; differentially expressed ... See more keywords