Comparison of DNA fragmentation of frozen-thawed epididymal sperm of dogs using Sperm Chromatin Structure Analysis and Sperm Chromatin Dispersion test.
Sign Up to like & getrecommendations! Published in 2017 at "Animal reproduction science"
DOI: 10.1016/j.anireprosci.2017.10.007
Abstract: The aim of this study was to compare sperm DNA fragmentation of frozen-thawed epididymal sperm of dogs using the SCSA (Sperm Chromatin Structure Assay) and SCDt (Sperm Chromatin Dispersion test). For this purpose, epididymis from… read more here.
Keywords: sperm chromatin; fragmentation; dna fragmentation;
Role of Disulfide Bonds on DNA Packaging Forces in Bull Sperm Chromatin.
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical journal"
DOI: 10.1016/j.bpj.2017.08.050
Abstract: Short arginine-rich proteins called protamines mediate the near crystalline DNA packaging in most vertebrate sperm cells. Protamines are synthesized during spermiogenesis and condense the paternal genome into a transcriptionally inactive state in late-stage spermatids. Protamines… read more here.
Keywords: disulfide bonds; dna packaging; bonds dna; role disulfide ... See more keywords
Condensation and protamination of sperm chromatin affect ICSI outcomes when gametes from healthy individuals are used.
Sign Up to like & getrecommendations! Published in 2022 at "Human reproduction"
DOI: 10.1093/humrep/deac261
Abstract: STUDY QUESTION Do defects in sperm chromatin protamination and condensation have an impact on ICSI outcomes? SUMMARY ANSWER Sperm protamination is related to fertilization rates in healthy donors, and the in vitro capacity of sperm… read more here.
Keywords: female age; sperm chromatin; age; cohort ... See more keywords
Diagnostics of DNA fragmentation in human spermatozoa: Are sperm chromatin structure analysis and sperm chromatin dispersion tests (SCD‐HaloSpermG2®) comparable?
Sign Up to like & getrecommendations! Published in 2019 at "Andrologia"
DOI: 10.1111/and.13316
Abstract: Men affected with idiopathic infertility often display basic spermiogramme values similar to fertile individuals, questioning the diagnostic impact of the World Health Organization (WHO) thresholds used. This study explored sperm DNA fragmentation in single ejaculates… read more here.
Keywords: chromatin; chromatin structure; sperm chromatin; dna fragmentation ... See more keywords
Unravelling how in vitro capacitation alters ram sperm chromatin before and after cryopreservation
Sign Up to like & getrecommendations! Published in 2020 at "Andrology"
DOI: 10.1111/andr.12900
Abstract: Sperm chromatin structure provides valuable information for the prediction of male fertility and can be altered during different procedures. Previous studies have shown that sperm chromatin condensation decreased during in vitro capacitation. Moreover, cryopreservation can… read more here.
Keywords: chromatin; unravelling vitro; vitro capacitation; cryopreservation ... See more keywords
Analysis of sperm chromatin packaging and reproductive biomarker to evaluate the consequence of advanced male age
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2023.1092603
Abstract: In this study, the semen parameters, sperm chromatin integrity, antioxidant enzyme levels, and reproductive hormone levels of subfertile male subjects from Pakistan were assessed in relation to their age. Data on the demographic characteristics of… read more here.
Keywords: group; male age; sperm chromatin; age ... See more keywords
A Molecular Mechanism to Explain the Nickel-Induced Changes in Protamine-like Proteins and Their DNA Binding Affecting Sperm Chromatin in Mytilus galloprovincialis: An In Vitro Study
Sign Up to like & getrecommendations! Published in 2023 at "Biomolecules"
DOI: 10.3390/biom13030520
Abstract: Nickel is associated with reproductive toxicity, but little is known about the molecular mechanisms of nickel-induced effects on sperm chromatin and protamine-like proteins (PLs). In the present work, we analyzed PLs from Mytilus galloprovincialis by… read more here.
Keywords: nickel induced; like proteins; protamine like; sperm chromatin ... See more keywords
Sperm Chromatin Condensation Defect Accelerates the Kinetics of Early Embryonic Development but Does Not Modify ICSI Outcome
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010393
Abstract: The origin and quality of gametes are likely to influence the kinetics of embryonic development. The purpose of the study was to assess the impact of sperm nuclear quality, and in particular sperm chromatin condensation,… read more here.
Keywords: embryonic development; condensation; sperm chromatin; chromatin condensation ... See more keywords