Sperm‐derived RNAs improve the efficiency of somatic cell nuclear transfer (SCNT) through promoting R‐loop formation
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DOI: 10.1002/mrd.23627
Abstract: Mammalian sperm and oocytes are haploid cells that carry parental genetic and epigenetic information for their progeny. The cytoplasm of oocytes is also capable of reprograming somatic cells to establish totipotency through somatic cell nuclear… read more here.
Keywords: sperm derived; somatic cell; cell nuclear; sperm ... See more keywords
CpG methylation participates in regulation of hepatitis B virus gene expression in host sperm and sperm-derived embryos.
Sign Up to like & getrecommendations! Published in 2017 at "Epigenomics"
DOI: 10.2217/epi-2016-0129
Abstract: AIM This study was undertaken to investigate relationship between hepatitis B virus (HBV) CpG methylation and HBV gene transcription in sperm and sperm-derived embryos. METHODS HBV-infected patient sperm and HBV plasmid-transfected donor sperm were subjected… read more here.
Keywords: methylation; sperm sperm; sperm; sperm derived ... See more keywords
Sperm-Derived Dysfunction of Human Embryos: Molecular Mechanisms and Clinical Resolution
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DOI: 10.3390/ijms26136217
Abstract: In addition to the male genome, the fertilizing spermatozoon delivers to the oocyte several factors whose deficiency can cause embryo dysfunction. Sperm oocyte-activating factor, identified as phoshoplipase C zeta (PLCζ), drives oocyte exit from meiotic… read more here.
Keywords: sperm derived; dysfunction; human embryos; dna fragmentation ... See more keywords