Optimization of sperm RNA processing for developmental research
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-68486-1
Abstract: Recent studies have demonstrated the significance of sperm RNA function as a transporter of important information directing the course of life. To determine the message contained in sperm RNA, it is necessary to optimize transcriptomic… read more here.
Keywords: research; sperm rna; processing; rna ... See more keywords
All you need to know about sperm RNAs.
Sign Up to like & getrecommendations! Published in 2021 at "Human reproduction update"
DOI: 10.1093/humupd/dmab034
Abstract: BACKGROUND Spermatogenesis generates a small and highly specialised type of cell that is apparently incapable of transcription and translation. For many years, this dogma was supported by the assumption that (i) the compact sperm nucleus,… read more here.
Keywords: sperm rna; know sperm; rna; sperm rnas ... See more keywords
Sperm RNA preparation for transcriptomic analysis: Review of the techniques and personal experience
Sign Up to like & getrecommendations! Published in 2017 at "Andrologia"
DOI: 10.1111/and.12767
Abstract: In the last 10 years, several approaches, including microarrays, have been applied to investigate sperm transcript levels. However, success using microarray profiling is highly dependent of the quality of the RNA obtained. Therefore, the development… read more here.
Keywords: sperm rna; rna preparation; rna; transcriptomic analysis ... See more keywords
Trans Species RNA Activity: Sperm RNA of the Father of an Autistic Child Programs Glial Cells and Behavioral Disorders in Mice
Sign Up to like & getrecommendations! Published in 2024 at "Biomolecules"
DOI: 10.3390/biom14020201
Abstract: Recently, we described the alteration of six miRNAs in the serum of autistic children, their fathers, mothers, siblings, and in the sperm of autistic mouse models. Studies in model organisms suggest that noncoding RNAs participate… read more here.
Keywords: father autistic; rna; trans species; glial cells ... See more keywords
Sperm RNA Payload: Implications for Intergenerational Epigenetic Inheritance
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24065889
Abstract: There is mounting evidence that ancestral life experiences and environment can influence phenotypes in descendants. The parental environment regulates offspring phenotypes potentially via modulating epigenetic marks in the gametes. Here, we review examples of across-generational… read more here.
Keywords: payload implications; inheritance; implications intergenerational; rna payload ... See more keywords
Sperm RNA quantity and PRM1, PRM2, and TH2B transcript levels reflect sperm characteristics and early embryonic development
Sign Up to like & getrecommendations! Published in 2024 at "Asian Journal of Andrology"
DOI: 10.4103/aja202452
Abstract: Spermatozoa have a highly complex RNA profile. Several of these transcripts are suggested as biomarkers for male infertility and contribute to early development. To analyze the differences between sperm RNA quantity and expression of protamine… read more here.
Keywords: prm1 prm2; development; sperm characteristics; sperm rna ... See more keywords