Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.109787
Abstract: Paternal exposure to environmental stressors elicits distinct changes to the sperm sncRNA profile, modifications that have significant post-fertilization consequences. Despite this knowledge, there remains limited mechanistic understanding of how paternal exposures modify the sperm sncRNA… read more here.
Keywords: epididymal proteome; acrylamide modulates; modulates mouse; sperm sncrna ... See more keywords
The Sperm Small RNA Transcriptome: Implications beyond Reproductive Disorder
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232415716
Abstract: Apart from the paternal half of the genetic material, the male gamete carries assorted epigenetic marks for optimal fertilization and the developmental trajectory for the early embryo. Recent works showed dynamic changes in small noncoding… read more here.
Keywords: sperm small; implications beyond; sperm sncrna; transcriptome implications ... See more keywords