Mouse spermatogenesis‐associated protein 1 (SPATA1), an IFT20 binding partner, is an acrosomal protein
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Dynamics"
DOI: 10.1002/dvdy.141
Abstract: Intraflagellar transport is a motor‐driven trafficking system that is required for the formation of cilia. Intraflagellar transport protein 20 (IFT20) is a master regulator for the control of spermatogenesis and male fertility in mice. However,… read more here.
Keywords: protein; spermatogenesis; associated protein; spermatogenesis associated ... See more keywords
Cyclin‐dependent kinase 7 is essential for spermatogenesis by regulating retinoic acid signaling pathways and the STAT3 molecular pathway
Sign Up to like & getrecommendations! Published in 2021 at "IUBMB Life"
DOI: 10.1002/iub.2574
Abstract: Spermatogenesis is a complex process that requires precise regulation. Phosphorylation plays a role in spermatogenesis by regulating protein structure and activity. This study focused on cyclin‐dependent kinase 7 (CDK7), and explored its function and molecular… read more here.
Keywords: spermatogenesis; cdk7; cyclin dependent; dependent kinase ... See more keywords
Deficiency of fibroblast growth factor 2 (FGF‐2) leads to abnormal spermatogenesis and altered sperm physiology
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26876
Abstract: In previous studies, we described the presence of fibroblast growth factor 2 (FGF‐2) and its receptors (FGFRs) in human testis and sperm, which are involved in spermatogenesis and in motility regulation. The aim of the… read more here.
Keywords: spermatogenesis; fgf; fibroblast growth; growth factor ... See more keywords
HFD-fed mice appeared more severe spermatogenesis impairment by lead exposure: perspective from gut microbiota and the efficacy of probiotics.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12309
Abstract: BACKGROUND The mechanism of multifactorial spermatogenesis impairment is unclear. This study aims to investigate the reproductive toxicity of Pb in high-fat diet (HFD)-fed mice, and delineate the important role of gut microbiota. RESULTS Results showed… read more here.
Keywords: hfd fed; spermatogenesis; fed mice; gut microbiota ... See more keywords
Insights into in vitro spermatogenesis in mammals: Past, present, future
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.22819
Abstract: Considering the self‐renewal and differentiation ability of pluripotent stem cells, some studies have pointed out the possibility of stem cell‐derived sperm production. Most studies that test this hypothesis have been conducted on rodents, with some… read more here.
Keywords: spermatogenesis; stem cells; vitro spermatogenesis; insights vitro ... See more keywords
Jun‐mediated lncRNA‐IMS promotes the meiosis of chicken spermatogonial stem cells via gga‐miR‐31‐5p/stra8
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23682
Abstract: Meiosis, a key step in spermatogenesis, is affected by many factors. Current studies have shown that long noncoding RNAs (lncRNAs) are potential factors regulating meiosis, and their regulatory mechanisms have received much attention. However, little… read more here.
Keywords: spermatogenesis; meiosis; gga mir; stra8 ... See more keywords
NBMA Promotes Spermatogenesis by Mediating Oct4 Pathway
Sign Up to like & getrecommendations! Published in 2022 at "ChemistryOpen"
DOI: 10.1002/open.202100219
Abstract: Abstract Non‐obstructive azoospermia is one of the most common causes of male infertility, but there is still no specific treatment drug. Given that the Oct4 (Octamer‐binding transcription factor 4) has an important regulatory effect on… read more here.
Keywords: spermatogenesis; promotes spermatogenesis; spermatogenesis mediating; oct4 pathway ... See more keywords
Azadirachtin-based insecticide impairs testis morphology and spermatogenesis of the southern armyworm Spodoptera eridania (Lepidoptera: Noctuidae).
Sign Up to like & getrecommendations! Published in 2022 at "Pest management science"
DOI: 10.1002/ps.7338
Abstract: BACKGROUND In the search for alternative tools for integrated pest management, azadirachtin, a botanical insecticide, has been used with the most promising activity against Spodoptera spp., but the mechanism of cytotoxicity on reproductive organs remains… read more here.
Keywords: spermatogenesis; azadirachtin; morphology; spodoptera eridania ... See more keywords
Androgen Actions in the Testis and the Regulation of Spermatogenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-77779-1_9
Abstract: Testosterone is essential for spermatogenesis and male fertility. In this review, topics related to testosterone control of spermatogenesis are covered including testosterone production and levels in the testis, classical and nonclassical testosterone signaling pathways, cell-… read more here.
Keywords: spermatogenesis; actions testis; androgen actions; testosterone ... See more keywords
Exogenous Androgens and Male Reproduction.
Sign Up to like & getrecommendations! Published in 2017 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-319-69535-8_4
Abstract: Due in part to aggressive marketing, the prevalence of exogenous androgen use has increased to disturbing levels. Prescribing practitioners are often unaware of the severity of the anti-fertility effects. Exogenous androgens should only be prescribed… read more here.
Keywords: spermatogenesis; exogenous androgens; testosterone; male reproduction ... See more keywords
Spermatogenic failure and the Y chromosome
Sign Up to like & getrecommendations! Published in 2017 at "Human Genetics"
DOI: 10.1007/s00439-017-1793-8
Abstract: The Y chromosome harbors a number of genes essential for testis development and function. Its highly repetitive structure predisposes this chromosome to deletion/duplication events and is responsible for Y-linked copy-number variations (CNVs) with clinical relevance. The… read more here.
Keywords: failure chromosome; spermatogenesis; spermatogenic failure; deletion ... See more keywords