TOP-2 is differentially required for the proper maintenance of the cohesin subunit REC-8 on meiotic chromosomes in C. elegans spermatogenesis and oogenesis.
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DOI: 10.1093/genetics/iyac120
Abstract: During meiotic prophase I, accurate segregation of homologous chromosomes requires the establishment of chromosomes with a meiosis-specific architecture. The sister chromatid cohesin complex and the enzyme Topoisomerase II are important components of meiotic chromosome architecture,… read more here.
Keywords: cohesin subunit; spermatogenesis oogenesis; subunit rec; chromosome ... See more keywords
Rad21l1 cohesin subunit is dispensable for spermatogenesis but not oogenesis in zebrafish
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DOI: 10.1371/journal.pgen.1009127
Abstract: During meiosis I, ring-shaped cohesin complexes play important roles in aiding the proper segregation of homologous chromosomes. RAD21L is a meiosis-specific vertebrate cohesin that is required for spermatogenesis in mice but is dispensable for oogenesis… read more here.
Keywords: rad21l1; cohesin; spermatogenesis oogenesis; cohesin subunit ... See more keywords