Augmentation of progestin signaling rescues testis organization and spermatogenesis in zebrafish with the depletion of androgen signaling
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DOI: 10.7554/elife.66118
Abstract: Disruption of androgen signaling is known to cause testicular malformation and defective spermatogenesis in zebrafish. However, knockout of cyp17a1, a key enzyme responsible for the androgen synthesis, in ar-/- male zebrafish paradoxically causes testicular hypertrophy… read more here.
Keywords: spermatogenesis; cyp17a1; progestin; spermatogenesis zebrafish ... See more keywords