Regulation of fibroblast growth factor 8 (FGF8) in chicken embryonic stem cells differentiation into spermatogonial stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26402
Abstract: Fibroblast growth factors (FGFs) are essential in regulating the formation of spermatogonial stem cells (SSCs). Here, we explored the effect of FGF8 on chicken SSCs formation by knockdown or overexpression of FGF8 in chicken embryonic… read more here.
Keywords: stem cells; spermatogonial stem; fibroblast growth; stem ... See more keywords
In silico analysis of single‐cell RNA sequencing data from 3 and 7 days old mouse spermatogonial stem cells to identify their differentially expressed genes and transcriptional regulators
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27066
Abstract: Spermatogonial stem cells (SSCs), which are at the basis of spermatogenesis process, are valuable cells with different applications in biotechnology and regenerative medicine. Understanding the molecular basis of SSC self‐renewal and differentiation at various developmental… read more here.
Keywords: days old; single cell; spermatogonial stem; cell rna ... See more keywords
Noncoding RNAs: Potential players in the self‐renewal of mammalian spermatogonial stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23041
Abstract: Spermatogonial stem cells (SSCs), a unique population of male germ cells with self‐renewal ability, are the foundation for maintenance of spermatogenesis throughout the life of the male. Although many regulatory molecules essential for SSC self‐renewal… read more here.
Keywords: spermatogonial stem; renewal; self renewal; ssc self ... See more keywords
Expression pattern of alkB homolog 5 in goat testis and its role in spermatogonial stem cells.
Sign Up to like & getrecommendations! Published in 2021 at "Cell and tissue research"
DOI: 10.1007/s00441-021-03550-4
Abstract: RNA N6-methyladenosine (m6A) is essential for many bioprocesses in many species, but its role in goat testis development remains elusive, especially alkB homolog 5 (ALKBH5), one of the m6A demethylases. To this end, nine healthy… read more here.
Keywords: spermatogonial stem; goat testis; goat; role ... See more keywords
Effect of NMDA receptor agonist and antagonist on spermatogonial stem cells proliferation in 2- and 3- dimensional culture systems.
Sign Up to like & getrecommendations! Published in 2022 at "Molecular biology reports"
DOI: 10.1007/s11033-021-07041-1
Abstract: BACKGROUND The main purpose of this study was to investigate the effect of D-serine (DS) and Dizocilpine (MK-801) on the proliferation of spermatogonial stem cells (SSCs) in two-dimensional (2D) and three-dimensional (3D) culture systems. METHODS… read more here.
Keywords: culture; spermatogonial stem; dimensional culture; stem cells ... See more keywords
Spermatogonial stem cell transplantation and male infertility: Current status and future directions
Sign Up to like & getrecommendations! Published in 2018 at "Arab Journal of Urology"
DOI: 10.1016/j.aju.2017.11.015
Abstract: Abstract Objective: To summarise the current state of research into spermatogonial stem cell (SSC) therapies with a focus on future directions, as SSCs show promise as a source for preserving or initiating fertility in otherwise… read more here.
Keywords: spermatogonial stem; stem cell; male infertility;
A single-cell view of spermatogonial stem cells.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in cell biology"
DOI: 10.1016/j.ceb.2020.07.005
Abstract: Spermatogonial stem cells (SSCs) are essential for long-term spermatogenesis and are the subject of considerable clinical interest, as 'SSC therapy' has the potential to cure some forms of male infertility. Recently, we have learned more… read more here.
Keywords: single cell; cell; spermatogonial stem; cell view ... See more keywords
Metabolic Changes Accompanying Spermatogonial Stem Cell Differentiation.
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DOI: 10.1016/j.devcel.2020.01.014
Abstract: Male fertility is driven by spermatogonial stem cells (SSCs) that self-renew while also giving rise to differentiating spermatogonia. Spermatogonial transitions are accompanied by a shift in gene expression, however, whether equivalent changes in metabolism occur… read more here.
Keywords: accompanying spermatogonial; metabolic changes; spermatogonial stem; changes accompanying ... See more keywords
Unique Epigenetic Programming Distinguishes Regenerative Spermatogonial Stem Cells in the Developing Mouse Testis
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DOI: 10.1016/j.isci.2020.101596
Abstract: Summary Spermatogonial stem cells (SSCs) both self-renew and give rise to progenitors that initiate spermatogenic differentiation in the mammalian testis. Questions remain regarding the extent to which the SSC and progenitor states are functionally distinct.… read more here.
Keywords: testis; epigenetic programming; spermatogonial stem; unique epigenetic ... See more keywords
The applications and recovery outcome of spermatogonia stem cells in regenerative medicine
Sign Up to like & getrecommendations! Published in 2017 at "Middle East Fertility Society Journal"
DOI: 10.1016/j.mefs.2017.05.008
Abstract: Abstract Spermatogonial stem cells are unique cells that line the basal lamina of seminiferous tubules in the testis and have the potential of self-renewal and differentiation. These cells pass on genetic information to the next… read more here.
Keywords: medicine; spermatogonial stem; cells regenerative; stem ... See more keywords
Culture and transplantation of spermatogonial stem cells.
Sign Up to like & getrecommendations! Published in 2018 at "Stem cell research"
DOI: 10.1016/j.scr.2018.03.006
Abstract: The spermatogonial transplantation technique was developed by Dr. Ralph Brinster in 1994. Transplanted spermatogonial stem cells (SSCs) produce germ cell colonies after microinjection into the seminiferous tubules of infertile mice. This technique provided the first… read more here.
Keywords: technique; spermatogonial stem; transplantation; stem ... See more keywords