Serum Compatible Spermine‐Based Cationic Lipids with Nonidentical Hydrocarbon Tails Mediate High Transfection Efficiency
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202100672
Abstract: Cationic lipids are widely used as nonviral synthetic vectors for gene delivery as a safer alternative to viral vectors. In this work, a library of L‐shaped spermine‐based cationic lipids with identical and nonidentical hydrophobic chains… read more here.
Keywords: nonidentical hydrocarbon; spermine based; based cationic; cationic lipids ... See more keywords
Spermine‐Based Nanocarriers for siRNA Delivery in Fibroblast‐Driven Diseases: A Proof‐of‐Concept Study
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DOI: 10.1002/macp.202500295
Abstract: The development of nanocarriers for nucleic acid delivery has gained significant attention as a promising strategy to regulate protein expression. Small interfering RNA (siRNA) is a powerful tool for gene silencing; however, it is rapidly… read more here.
Keywords: sirna delivery; delivery; nanocarriers sirna; based nanocarriers ... See more keywords
Simple fluorescence optosensing probe for spermine based on ciprofloxacin-Tb3+ complexation
Sign Up to like & getrecommendations! Published in 2021 at "PLoS ONE"
DOI: 10.1371/journal.pone.0251306
Abstract: We developed a facile detection method of spermine based on the fluorescence (FL) quenching of the ciprofloxacin-Tb3+ complex, which shows astrong green emission. Ciprofloxacin (CP) makes efficient bondings to Tb3+ ion as a linker molecule… read more here.
Keywords: spermine; fluorescence; probe; spermine based ... See more keywords