Effect of long-term treatment with classical neuroleptics on NPQ/spexin, kisspeptin and POMC mRNA expression in the male rat amygdala
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-018-1868-2
Abstract: Neuroleptics modulate the expression level of some regulatory neuropeptides in the brain. However, if these therapeutics influence the peptidergic circuits in the amygdala remains unclear. This study specifies the impact profile of the classical antipsychotic… read more here.
Keywords: rat amygdala; spexin; kisspeptin pomc; expression ... See more keywords
Spexin as an anxiety regulator in mouse hippocampus: Mechanisms for transcriptional regulation of spexin gene expression by corticotropin releasing factor.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.02.023
Abstract: Spexin (SPX) acts as a neuropeptide with pleiotropic functions that can participate in anxiety regulation. Corticotropin releasing factor (CRF) is widely expressed in brain tissues and associated with depression and anxiety and addiction. With the… read more here.
Keywords: releasing factor; spexin; anxiety; corticotropin releasing ... See more keywords
The effect of umbilical cord blood spexin, free 25(OH) vitamin D3 and adipocytokine levels on intrauterine growth and anthropometric measurements in newborns.
Sign Up to like & getrecommendations! Published in 2021 at "Cytokine"
DOI: 10.1016/j.cyto.2021.155578
Abstract: Spexin is a newly described peptide and is known to reduce the uptake of long-chain fatty acids into adipocytes. The serum spexin levels of obese children between the ages of 12-18 are lower. The effect… read more here.
Keywords: free vitamin; effect; cord blood; spexin ... See more keywords
Distribution and neuronal circuit of spexin 1/2 neurons in the zebrafish CNS
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-41431-7
Abstract: Spexin (SPX) is a highly conserved neuropeptide that is widely expressed in mammalian brain and peripheral tissue. In teleost, SPX1 is mainly expressed in the brain and ovary, and is involved in reproduction and food… read more here.
Keywords: spexin; distribution neuronal; expression; spx1 neurons ... See more keywords
Dual Role of Insulin in Spexin Regulation: Functional Link Between Food Intake and Spexin Expression in a Fish Model
Sign Up to like & getrecommendations! Published in 2017 at "Endocrinology"
DOI: 10.1210/en.2016-1534
Abstract: Spexin (SPX), a neuropeptide discovered by the bioinformatics approach, has been recently identified as a satiety factor in a fish model. However, the functional link between feeding and SPX expression as well as the signal… read more here.
Keywords: insulin; spexin; spx; model ... See more keywords
Serum spexin differed in newly diagnosed type 2 diabetes patients according to body mass index and increased with the improvement of metabolic status
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.1086497
Abstract: Objective The aim of this study was to explore serum spexin levels in newly diagnosed type 2 diabetes mellitus (T2DM) patients with different body mass indexes (BMIs) and to investigate the changes of spexin after… read more here.
Keywords: spexin; newly diagnosed; serum spexin; group ... See more keywords
Overexpression of Spexin 1 in the Dorsal Habenula Reduces Anxiety in Zebrafish
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2019.00053
Abstract: Spexin (SPX) is an evolutionarily conserved neuropeptide that is expressed in the mammalian brain and peripheral tissue. Two orthologs are present in the teleost, SPX1 and SPX2. SPX1 is involved in reproduction and food intake.… read more here.
Keywords: dhb; dorsal habenula; spx1; spexin ... See more keywords
Spexin mRNA profile and its response to different photoperiods in Chinese Yangzhou geese (Anas cygnoides)
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2022.961431
Abstract: Spexin (SPX, NPQ), a novel neuropeptide composed of 14 amino acid residues, is evolutionarily conserved among different species. Spexin has been suggested to have pleiotropic functions in mammals. However, reports on spexin in birds are… read more here.
Keywords: spexin; response different; spexin mrna; different photoperiods ... See more keywords
Comparing serum concentration of spexin among patients with metabolic syndrome, healthy overweight/obese, and normal-weight individuals
Sign Up to like & getrecommendations! Published in 2019 at "Medical Journal of the Islamic Republic of Iran"
DOI: 10.34171/mjiri.33.93
Abstract: Background: There are many factors related to etiology of metabolic syndrome (MetS) including obesity. Spexin, a peptide hormone released from adipose tissue, is the most down-regulated gene in obese, compared to non-obese adipose tissue. Hence,… read more here.
Keywords: overweight obese; spexin; concentration spexin; serum concentration ... See more keywords