Gut commensals suppress interleukin-2 production through microRNA-200/BCL11B and microRNA-200/ETS-1 axes in lamina propria leukocytes of murine large intestine.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.10.103
Abstract: The role of microRNAs (miRNAs) in how microbiota influence the host intestinal immune system is not fully understood. We compared the expression profiles of miRNAs and mRNAs in lamina propria leukocytes (LPL) in the large… read more here.
Keywords: production; microrna 200; spf mice; lamina propria ... See more keywords
Short communication: Gut microbial colonization of the mouse colon using faecal transfer was equally effective when comparing rectal inoculation and oral inoculation based on 16S rRNA sequencing.
Sign Up to like & getrecommendations! Published in 2019 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2019.09.009
Abstract: In the present study we hypothesized that a higher degree of gut microbiota (GM) transfer and colonization could be reached by rectal inoculation compared to oral inoculation, which is commonly used in mouse studies for… read more here.
Keywords: inoculation; spf mice; colon; 16s rrna ... See more keywords
677 Evaluation of anti-PD1 efficacy in germ-free and antibiotic-treated SPF mice bearing MC38 tumors
Sign Up to like & getrecommendations! Published in 2020 at "Journal for ImmunoTherapy of Cancer"
DOI: 10.1136/jitc-2020-sitc2020.0677
Abstract: Background Increasing evidence has indicated the important role of gut microbes in mediating normal and pathologic immune responses to cancer in both patients and animal models. There is growing effort in modulating microbiota composition to… read more here.
Keywords: antibiotic treated; spf mice; efficacy; germ free ... See more keywords
Intestinal Microbiota and Serum Metabolic Profile Responded to Two Nutritional Different Diets in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2021.813757
Abstract: There is an interaction and bidirectional selection between dietary intake and gut microbiota due to the different efficiency of nutrients in the gut. The nutritional composition of germ-free (GF) diets differs significantly from specific pathogen-free… read more here.
Keywords: serum metabolic; microbiota; spf mice; metabolic profile ... See more keywords