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   Articles with "sphere formation" as a keyword



SDF-1/CXCR4 axis promotes the growth and sphere formation of hypoxic breast cancer SP cells by c-Jun/ABCG2 pathway.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.09.130

Abstract: ATP-binding cassette sub-family G member 2 (ABCG2) confers to the major phenotypes of side population (SP) cells, the cancer stem-like cells. In this study, the SP cells displayed a distinctly higher ABCG2 expression level, sphere… read more here.

Keywords: sphere formation; breast cancer; hypoxic; cancer ... See more keywords
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Neuregulin-1-β1 and γ-secretase play a critical role in sphere-formation and cell survival of urothelial carcinoma cancer stem-like cells.

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recommendations! Published in 2021 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2021.03.038

Abstract: Previously, we investigated gene expression in a high aldehyde dehydrogenase 1 expression (ALDH1high) population of urothelial carcinoma (UC) cells as UC cancer stem-like cells (CSCs)/cancer-initiating cells (CICs) and found that NRG1 expression was upregulated in… read more here.

Keywords: role sphere; sphere formation; role; cancer ... See more keywords

Single-Cell Tracking of Breast Cancer Cells Enables Prediction of Sphere Formation from Early Cell Divisions

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recommendations! Published in 2018 at "iScience"

DOI: 10.1016/j.isci.2018.08.015

Abstract: Summary The mammosphere assay has become widely employed to quantify stem-like cells in a population. However, the problem is there is no standard protocol employed by the field. Cell seeding densities of 1,000 to 100,000… read more here.

Keywords: single cell; breast; early cell; sphere formation ... See more keywords

Neuroblastoma stem cells and CFC1

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recommendations! Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.18491

Abstract: Cancer stem cells (CSCs) have been implicated in many cancers and build up an intratumor heterogeneity bestowing multiple competences on the tumor for metastasis and resistance to anti-cancer drugs [1]. Neuroblastoma is a childhood cancer… read more here.

Keywords: cfc1; sphere formation; neuroblastoma; formation ... See more keywords

STAT1-HDAC4 signaling induces epithelial-mesenchymal transition and sphere formation of cancer cells overexpressing the oncogene, CUG2

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recommendations! Published in 2018 at "Oncology Reports"

DOI: 10.3892/or.2018.6701

Abstract: Our previous studies have shown that the novel oncogene, cancer upregulated gene 2 (CUG2), activates STAT1, which is linked to anticancer drug resistance, induces epithelial-mesenchymal transition (EMT) and cancer stem cell-like phenotypes as determined by… read more here.

Keywords: cug2; hdac4; sphere formation; stat1 ... See more keywords