Tumour spheres with inverted polarity drive the formation of peritoneal metastases in patients with hypermethylated colorectal carcinomas
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DOI: 10.1038/s41556-017-0027-6
Abstract: Metastases account for 90% of cancer-related deaths; thus, it is vital to understand the biology of tumour dissemination. Here, we collected and monitored >50 patient specimens ex vivo to investigate the cell biology of colorectal… read more here.
Keywords: spheres inverted; tumour spheres; topology; biology ... See more keywords