Spheroid-on-chip microfluidic technology for the evaluation of the impact of continuous flow on metastatic potential in cancer models in vitro.
Sign Up to like & getrecommendations! Published in 2021 at "Biomicrofluidics"
DOI: 10.1063/5.0061373
Abstract: The majority of cancer deaths are linked to tumor spread, or metastasis, but 3D in vitro metastasis models relevant to the tumor microenvironment (including interstitial fluid flow) remain an area of unmet need. Microfluidics allows… read more here.
Keywords: spheroid chip; interstitial fluid; metastasis; cancer ... See more keywords
Computational Modelling and Big Data Analysis of Flow and Drug Transport in Microfluidic Systems: A Spheroid-on-a-Chip Study
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2021.781566
Abstract: Microfluidic tumour spheroid-on-a-chip platforms enable control of spheroid size and their microenvironment and offer the capability of high-throughput drug screening, but drug supply to spheroids is a complex process that depends on a combination of… read more here.
Keywords: spheroid chip; drug; device; chip ... See more keywords
A Cardiac Cell Outgrowth Assay for Evaluating Drug Compounds Using a Cardiac Spheroid-on-a-Chip Device
Sign Up to like & getrecommendations! Published in 2018 at "Bioengineering"
DOI: 10.3390/bioengineering5020036
Abstract: Three-dimensional (3D) models with cells arranged in clusters or spheroids have emerged as valuable tools to improve physiological relevance in drug screening. One of the challenges with cells cultured in 3D, especially for high-throughput applications,… read more here.
Keywords: spheroid chip; cardiac cell; cell outgrowth; drug ... See more keywords