Human serum alters cell culture behavior and improves spheroid formation in comparison to fetal bovine serum
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Cell Research"
DOI: 10.1016/j.yexcr.2018.02.017
Abstract: Background The use of fetal bovine serum (FBS) as growth supplement for human cell and tissue culture is widely spread in basic research as well as in clinical approaches, although several limitations must be considered,… read more here.
Keywords: fetal bovine; serum; spheroid formation; culture ... See more keywords
Hepatic Spheroid Formation on Carbohydrate-Functionalized Supramolecular Hydrogels.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01390
Abstract: Two synthetic supramolecular hydrogels, formed from bis-urea amphiphiles containing lactobionic acid (LBA) and maltobionic acid (MBA) bioactive ligands, are applied as cell culture matrices in vitro. Their fibrillary and dynamic nature mimics essential features of… read more here.
Keywords: carbohydrate functionalized; spheroid formation; hepatic spheroid; supramolecular hydrogels ... See more keywords
Abstract 3080: ILEI regulates LIFR expression and CSC self-renewal
Sign Up to like & getrecommendations! Published in 2021 at "Tumor Biology"
DOI: 10.1158/1538-7445.am2021-3080
Abstract: Our lab has previously identified a mechanism of transforming growth factor beta (TGFβ)-mediated epithelial-to-mesenchymal transition (EMT) in normal murine mammary gland (NMuMG) cells. Reduced expression of heterogenous nuclear ribonucleoprotein E1 (hnRNP E1, hereafter “E1”) in… read more here.
Keywords: expression; ilei; spheroid formation; ilei lifr ... See more keywords
Abstract A06: Synthetic peptides derived from the cell adhesion molecule Nectin-4 inhibit the formation of ovarian cancer 3D spheroids
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cancer Research"
DOI: 10.1158/1557-3265.ovca19-a06
Abstract: A unique aspect of ovarian cancer progression is the collection of ascites fluid in the abdominal cavity, which contains free-floating tumor cells in the form of single cells and also multicellular aggregates or spheroids. Spheroids… read more here.
Keywords: formation; spheroid formation; ovarian cancer; cancer ... See more keywords
The Dopamine D2 Receptor Contributes to the Spheroid Formation Behavior of U87 Glioblastoma Cells
Sign Up to like & getrecommendations! Published in 2019 at "Pharmacology"
DOI: 10.1159/000502562
Abstract: Background: Glioblastoma multiforme (GBM) is a common and lethal cancer of the central nervous system. This cancer is difficult to treat because most anticancer therapeutics do not readily penetrate into the brain due to the… read more here.
Keywords: d2r; glioblastoma; formation; spheroid formation ... See more keywords
The oncogene KRAS promotes cancer cell dissemination by stabilizing spheroid formation via the MEK pathway
Sign Up to like & getrecommendations! Published in 2018 at "BMC Cancer"
DOI: 10.1186/s12885-018-4922-4
Abstract: BackgroundPeritoneal dissemination is a critical prognostic factor in ovarian cancer. Although stabilized spheroid formation promotes cancer cell peritoneal dissemination in ovarian cancer, the associated oncogenes are unknown. In this study, we assessed the role of… read more here.
Keywords: spheroid formation; id8 kras; cancer; cell ... See more keywords
Distribution of SiO2 nanoparticles in 3D liver microtissues
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s189888
Abstract: Introduction Nanoparticles (NPs) are used in numerous products in technical fields and biomedicine; their potential adverse effects have to be considered in order to achieve safe applications. Besides their distribution in tissues, organs, and cellular… read more here.
Keywords: microscopy; formation; spheroid formation; sio2 nps ... See more keywords
Spheroid formation of human keratinocyte: Balancing between cell-substrate and cell-cell interaction.
Sign Up to like & getrecommendations! Published in 2020 at "Clinical hemorheology and microcirculation"
DOI: 10.3233/ch-209217
Abstract: BACKGROUND The formation of spheroids is tightly regulated by intrinsic cell-cell and cell-substrate interactions. OBJECTIVE The chitosan (CS)-coating was applied to investigate the driven force directed the spheroid formation. METHODS The effects of CS on… read more here.
Keywords: formation; cell substrate; cell cell; spheroid formation ... See more keywords
miR-590-3p Targets Cyclin G2 and FOXO3 to Promote Ovarian Cancer Cell Proliferation, Invasion, and Spheroid Formation
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms20081810
Abstract: Ovarian cancer is the leading cause of death from gynecological cancers. MicroRNAs (miRNAs) are small, non-coding RNAs that interact with the 3′ untranslated region (3′ UTR) of target genes to repress their expression. We have… read more here.
Keywords: spheroid formation; mir 590; ovarian cancer; ccng2 ... See more keywords
Inhibition of Ovarian Cancer Cell Spheroid Formation by Synthetic Peptides Derived from Nectin-4
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21134637
Abstract: The formation of 3D multicellular spheroids in the ascites fluid of ovarian cancer patients is an understudied component of the disease progression. Spheroids are less sensitive to chemotherapy, in part due to the protection afforded… read more here.
Keywords: formation; spheroid formation; ovarian cancer; cancer ... See more keywords
Spheroid Formation and Peritoneal Metastasis in Ovarian Cancer: The Role of Stromal and Immune Components
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116215
Abstract: Ovarian cancer (OC) is one of the most common gynecological cancers, with the worst prognosis and the highest mortality rate. Peritoneal dissemination (or carcinomatosis) accompanied by ascites formation is the most unfavorable factor in the… read more here.
Keywords: spheroid formation; stromal immune; ovarian cancer; immune components ... See more keywords